Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3662627..3663294 Replicon chromosome
Accession NZ_CP106885
Organism Achromobacter spanius strain LIG3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8Z00_RS16520 Protein ID WP_268077631.1
Coordinates 3662627..3663046 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8Z00_RS16525 Protein ID WP_268077632.1
Coordinates 3663043..3663294 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8Z00_RS16495 (N8Z00_16495) 3658381..3659340 - 960 WP_268077626.1 DMT family transporter -
N8Z00_RS16500 (N8Z00_16500) 3659422..3660291 - 870 WP_268077627.1 AraC family transcriptional regulator -
N8Z00_RS16505 (N8Z00_16505) 3660378..3661652 - 1275 WP_268077628.1 RNA polymerase sigma factor -
N8Z00_RS16510 (N8Z00_16510) 3661649..3662056 - 408 WP_268077629.1 VOC family protein -
N8Z00_RS16515 (N8Z00_16515) 3662075..3662485 - 411 WP_268077630.1 YciI family protein -
N8Z00_RS16520 (N8Z00_16520) 3662627..3663046 - 420 WP_268077631.1 type II toxin-antitoxin system VapC family toxin Toxin
N8Z00_RS16525 (N8Z00_16525) 3663043..3663294 - 252 WP_268077632.1 Arc family DNA-binding protein Antitoxin
N8Z00_RS16530 (N8Z00_16530) 3663395..3663748 - 354 WP_268077633.1 YciI family protein -
N8Z00_RS16535 (N8Z00_16535) 3663912..3664895 - 984 WP_268077634.1 OmpA family protein -
N8Z00_RS16540 (N8Z00_16540) 3664892..3665791 - 900 WP_268077635.1 MotA/TolQ/ExbB proton channel family protein -
N8Z00_RS16545 (N8Z00_16545) 3666089..3668056 + 1968 WP_268077636.1 NYN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(10-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14660.88 Da        Isoelectric Point: 4.8181

>T259933 WP_268077631.1 NZ_CP106885:c3663046-3662627 [Achromobacter spanius]
MILLDTNVISEPLRQAPADAVIEWIDRQPLETLFLSAVTVAELRFGVACMPVGKRRDALHGDLEQRVLALFAGRILAFDT
SASLEYVALMARARASGQAIGGPDGYIAATAAAHGMSVATRDVAPFEAAGVSVINPWGA

Download         Length: 420 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9284.64 Da        Isoelectric Point: 8.9326

>AT259933 WP_268077632.1 NZ_CP106885:c3663294-3663043 [Achromobacter spanius]
MPMLTVRNISEEVHRALRVRAAQHGRSTEAEVRAILEDAVKPEGRVKLGSLLLQIGRQARLTDEEAALFDQRDKAPAAPP
RFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References