Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1909794..1910321 Replicon chromosome
Accession NZ_CP106885
Organism Achromobacter spanius strain LIG3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8Z00_RS08605 Protein ID WP_268081220.1
Coordinates 1910046..1910321 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8Z00_RS08600 Protein ID WP_268081219.1
Coordinates 1909794..1910012 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8Z00_RS08570 (N8Z00_08570) 1905230..1905616 + 387 WP_268081213.1 DUF6152 family protein -
N8Z00_RS08575 (N8Z00_08575) 1905635..1906120 + 486 WP_268081214.1 DUF2214 domain-containing protein -
N8Z00_RS08580 (N8Z00_08580) 1906169..1906456 - 288 WP_268081215.1 cytochrome c -
N8Z00_RS08585 (N8Z00_08585) 1906557..1907795 - 1239 WP_268081216.1 sulfite oxidase -
N8Z00_RS08590 (N8Z00_08590) 1908045..1908992 - 948 WP_268081217.1 sensor domain-containing diguanylate cyclase -
N8Z00_RS08595 (N8Z00_08595) 1909010..1909468 - 459 WP_268081218.1 hypothetical protein -
N8Z00_RS08600 (N8Z00_08600) 1909794..1910012 + 219 WP_268081219.1 stability determinant Antitoxin
N8Z00_RS08605 (N8Z00_08605) 1910046..1910321 + 276 WP_268081220.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8Z00_RS08610 (N8Z00_08610) 1910348..1911337 - 990 WP_268082350.1 LysR family transcriptional regulator -
N8Z00_RS08615 (N8Z00_08615) 1911533..1912699 + 1167 WP_268082351.1 CoA transferase -
N8Z00_RS08620 (N8Z00_08620) 1912699..1913763 + 1065 WP_268081221.1 NADPH:quinone oxidoreductase family protein -
N8Z00_RS08625 (N8Z00_08625) 1913712..1914737 + 1026 WP_268081222.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10350.74 Da        Isoelectric Point: 5.0264

>T259931 WP_268081220.1 NZ_CP106885:1910046-1910321 [Achromobacter spanius]
MLPIFWSASALDDLDEITNYIAEYDVHAAIGMHELIENAVHPASEHPYLYRPGRVPGTREIVAHPNYILVYEVRADHIGV
IAVMHARQEYP

Download         Length: 276 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8234.24 Da        Isoelectric Point: 9.9898

>AT259931 WP_268081219.1 NZ_CP106885:1909794-1910012 [Achromobacter spanius]
MSPTLSPIVSEFETEEQAVSYDRWFRAKVQASRDDPRPSIPHDAAMARIREKLAKKLADHDAAPATRRSRDR

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References