Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1457578..1458092 Replicon chromosome
Accession NZ_CP106885
Organism Achromobacter spanius strain LIG3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N8Z00_RS06560 Protein ID WP_268080880.1
Coordinates 1457578..1457787 (+) Length 70 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8Z00_RS06565 Protein ID WP_268080881.1
Coordinates 1457784..1458092 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8Z00_RS06540 (N8Z00_06540) 1453084..1454100 + 1017 WP_268080876.1 amino acid ABC transporter substrate-binding protein -
N8Z00_RS06545 (N8Z00_06545) 1454226..1455416 + 1191 WP_268080877.1 amino acid ABC transporter permease -
N8Z00_RS06550 (N8Z00_06550) 1455418..1456518 + 1101 WP_268080878.1 amino acid ABC transporter permease -
N8Z00_RS06555 (N8Z00_06555) 1456579..1457319 + 741 WP_268080879.1 amino acid ABC transporter ATP-binding protein -
N8Z00_RS06560 (N8Z00_06560) 1457578..1457787 + 210 WP_268080880.1 hypothetical protein Toxin
N8Z00_RS06565 (N8Z00_06565) 1457784..1458092 + 309 WP_268080881.1 putative addiction module antidote protein Antitoxin
N8Z00_RS06570 (N8Z00_06570) 1458228..1459244 + 1017 WP_268080882.1 tripartite tricarboxylate transporter substrate binding protein -
N8Z00_RS06575 (N8Z00_06575) 1459666..1460841 - 1176 WP_268080883.1 ABC transporter substrate-binding protein -
N8Z00_RS06580 (N8Z00_06580) 1460888..1462120 - 1233 WP_268080884.1 3-hydroxybenzoate 6-monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-62)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-91)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7693.76 Da        Isoelectric Point: 7.9936

>T259930 WP_268080880.1 NZ_CP106885:1457578-1457787 [Achromobacter spanius]
MHGNFGDVEAVGEGVSEMRVSIGAGYRLYYARADELVYVLLCGGDKTSQARDIARAKRLWTDIKRSIEK

Download         Length: 210 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11085.49 Da        Isoelectric Point: 6.4652

>AT259930 WP_268080881.1 NZ_CP106885:1457784-1458092 [Achromobacter spanius]
MSKLRDFDAANYLKDDETIAHYLADAAAEDDPDAFLQALGDVARARGITEIARETGLARTNLYRVLAPGANPSYHTLRKV
MNALGVSLTALVRRKSDPTPQG

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References