Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 2443998..2444635 Replicon chromosome
Accession NZ_CP106878
Organism Fervidibacillus albus strain MEBiC13591

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag OE104_RS11790 Protein ID WP_275417026.1
Coordinates 2443998..2444348 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OE104_RS11795 Protein ID WP_275417027.1
Coordinates 2444354..2444635 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OE104_RS11775 (OE104_11785) 2440628..2441083 - 456 WP_275417023.1 SprT family protein -
OE104_RS11780 (OE104_11790) 2441253..2441366 + 114 WP_275417024.1 cortex morphogenetic protein CmpA -
OE104_RS11785 (OE104_11795) 2441607..2443787 - 2181 WP_275417025.1 Tex family protein -
OE104_RS11790 (OE104_11800) 2443998..2444348 - 351 WP_275417026.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OE104_RS11795 (OE104_11805) 2444354..2444635 - 282 WP_275417027.1 antitoxin endoai Antitoxin
OE104_RS11800 (OE104_11810) 2444781..2445932 - 1152 WP_275417028.1 alanine racemase -
OE104_RS11805 (OE104_11815) 2446104..2447126 - 1023 WP_275417029.1 outer membrane lipoprotein carrier protein LolA -
OE104_RS11810 (OE104_11820) 2447302..2447670 - 369 WP_275417030.1 holo-ACP synthase -
OE104_RS11815 (OE104_11825) 2447764..2448366 + 603 WP_275417031.1 rhomboid family intramembrane serine protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13052.16 Da        Isoelectric Point: 5.1961

>T259926 WP_275417026.1 NZ_CP106878:c2444348-2443998 [Fervidibacillus albus]
MIVKRGDVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEDMMEKVDEALRISMGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10666.13 Da        Isoelectric Point: 6.0837

>AT259926 WP_275417027.1 NZ_CP106878:c2444635-2444354 [Fervidibacillus albus]
VSESSVTQEILVSLPQSLLSEIDGYVKQENCNRDELIYQATKAFLHEKKKRHIRESMRRGYMEMAKINLSIAMEAIHAEY
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References