Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 2918777..2919414 Replicon chromosome
Accession NZ_CP106877
Organism Fervidibacillus halotolerans strain MEBiC13594

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OE105_RS13755 Protein ID WP_275420698.1
Coordinates 2919064..2919414 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OE105_RS13750 Protein ID WP_275420697.1
Coordinates 2918777..2919058 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OE105_RS13730 (OE105_13735) 2914998..2915588 - 591 WP_275420694.1 rhomboid family intramembrane serine protease -
OE105_RS13735 (OE105_13740) 2915685..2916041 + 357 WP_275420695.1 holo-ACP synthase -
OE105_RS13740 (OE105_13745) 2916248..2917270 + 1023 WP_275420696.1 outer membrane lipoprotein carrier protein LolA -
OE105_RS13745 (OE105_13750) 2917474..2918625 + 1152 WP_275422210.1 alanine racemase -
OE105_RS13750 (OE105_13755) 2918777..2919058 + 282 WP_275420697.1 antitoxin endoai Antitoxin
OE105_RS13755 (OE105_13760) 2919064..2919414 + 351 WP_275420698.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OE105_RS13760 (OE105_13765) 2919670..2921835 + 2166 WP_275422211.1 Tex family protein -
OE105_RS13765 (OE105_13770) 2922115..2922660 + 546 WP_275420699.1 sigma-70 family RNA polymerase sigma factor -
OE105_RS13770 (OE105_13775) 2922653..2924170 + 1518 WP_275420700.1 hypothetical protein -
OE105_RS13775 (OE105_13780) 2924273..2924386 - 114 WP_275420701.1 cortex morphogenetic protein CmpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13036.10 Da        Isoelectric Point: 5.1859

>T259925 WP_275420698.1 NZ_CP106877:2919064-2919414 [Fervidibacillus halotolerans]
MIVKRGDVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDDDMMEKVDESLRISLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10662.14 Da        Isoelectric Point: 5.6579

>AT259925 WP_275420697.1 NZ_CP106877:2918777-2919058 [Fervidibacillus halotolerans]
VSESGVTQEILVSLPQSLLSEIDGYVKQENCNRDELIYQATKAFLYEKKKRHIRESMRRGYMEMAKINLSIAMEAIHAEY
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References