Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4531093..4531640 Replicon chromosome
Accession NZ_CP106874
Organism Shewanella xiamenensis strain FH-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCF84_RS19825 Protein ID WP_188870826.1
Coordinates 4531093..4531395 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q8E8M1
Locus tag OCF84_RS19830 Protein ID WP_011074236.1
Coordinates 4531383..4531640 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCF84_RS19800 (OCF84_19820) 4526551..4527828 - 1278 WP_188870820.1 DUF5666 domain-containing protein -
OCF84_RS19805 (OCF84_19825) 4527918..4528586 + 669 WP_055646990.1 response regulator transcription factor -
OCF84_RS19810 (OCF84_19830) 4528558..4529850 + 1293 WP_188870822.1 HAMP domain-containing sensor histidine kinase -
OCF84_RS19815 (OCF84_19835) 4529941..4530330 + 390 WP_188870824.1 NirD/YgiW/YdeI family stress tolerance protein -
OCF84_RS19820 (OCF84_19840) 4530438..4530914 - 477 WP_037423763.1 peroxiredoxin -
OCF84_RS19825 (OCF84_19845) 4531093..4531395 - 303 WP_188870826.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCF84_RS19830 (OCF84_19850) 4531383..4531640 - 258 WP_011074236.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCF84_RS19835 (OCF84_19855) 4531781..4532110 - 330 WP_188870827.1 hypothetical protein -
OCF84_RS19840 (OCF84_19860) 4532369..4532830 - 462 WP_050991324.1 hypothetical protein -
OCF84_RS19845 (OCF84_19865) 4533137..4534057 - 921 WP_069453963.1 choice-of-anchor H family protein -
OCF84_RS19850 (OCF84_19870) 4534418..4534720 + 303 WP_037423775.1 peptidase M4 -
OCF84_RS19855 (OCF84_19875) 4534722..4535417 + 696 WP_037423778.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11846.85 Da        Isoelectric Point: 4.9119

>T259924 WP_188870826.1 NZ_CP106874:c4531395-4531093 [Shewanella xiamenensis]
MAEIIWTEPALADLNDIAEYIALENIVAAKQLVQMVFAKVERLVDFPDSGRIPPELERLNYREVVVNPCRVFYKYDDEKV
RILFVMRAERDLRRFMLTKQ

Download         Length: 303 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9675.21 Da        Isoelectric Point: 7.3181

>AT259924 WP_011074236.1 NZ_CP106874:c4531640-4531383 [Shewanella xiamenensis]
MKVELVTSLKRQATKILADLHETKEPVLITEHGKPSAYLIDVEDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDRM
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q8E8M1

References