259923

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 4267625..4268175 Replicon chromosome
Accession NZ_CP106874
Organism Shewanella xiamenensis strain FH-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCF84_RS18625 Protein ID WP_282895111.1
Coordinates 4267876..4268175 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID V1DMX4
Locus tag OCF84_RS18620 Protein ID WP_023266112.1
Coordinates 4267625..4267867 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCF84_RS18595 (OCF84_18605) 4262831..4264048 + 1218 WP_282895110.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -
OCF84_RS18600 (OCF84_18610) 4264054..4264596 + 543 WP_188870686.1 hotdog family protein -
OCF84_RS18605 (OCF84_18615) 4264697..4265422 + 726 WP_188870684.1 3-ketoacyl-ACP reductase FabG2 -
OCF84_RS18610 (OCF84_18620) 4265423..4266676 + 1254 WP_188870682.1 beta-ketoacyl-ACP synthase -
OCF84_RS18615 (OCF84_18625) 4266687..4267430 + 744 WP_188870680.1 hypothetical protein -
OCF84_RS18620 (OCF84_18630) 4267625..4267867 + 243 WP_023266112.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCF84_RS18625 (OCF84_18635) 4267876..4268175 + 300 WP_282895111.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCF84_RS18630 (OCF84_18640) 4269020..4269322 - 303 WP_282895112.1 hypothetical protein -
OCF84_RS18635 (OCF84_18645) 4269350..4269772 - 423 WP_282895113.1 AsnC family protein -
OCF84_RS18640 (OCF84_18650) 4269996..4270214 + 219 WP_282895114.1 hypothetical protein -
OCF84_RS18645 (OCF84_18655) 4270428..4271003 + 576 WP_282895115.1 hypothetical protein -
OCF84_RS18650 (OCF84_18660) 4271602..4272057 + 456 WP_169548263.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11500.23 Da        Isoelectric Point: 9.6431

>T259923 WP_282895111.1 NZ_CP106874:4267876-4268175 [Shewanella xiamenensis]
MNNKRYKLSRLAQAHLLKIKDYALQHFSESQWHKYQQSLISGLQMLADNPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQHHLK

Download         Length: 300 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8954.13 Da        Isoelectric Point: 4.7483

>AT259923 WP_023266112.1 NZ_CP106874:4267625-4267867 [Shewanella xiamenensis]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAQGNVVDGEDFLNAL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V1DMX4

References