Detailed information of TA system TA259921

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 2031578..2033294
• Replicon: chromosome
• Accession: NZ_CP106874
• Organism: Shewanella xiamenensis strain FH-1

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: OCF84_RS09085
• Protein ID: WP_257749920.1
• Coordinates: 2032359..2033294 (+)
• Length: 312 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: OCF84_RS09080
• Protein ID: WP_257749919.1
• Coordinates: 2031578..2032366 (+)
• Length: 263 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCF84_RS09065 (OCF84_09065)	2028400..2029635	+	1236	WP_188872259.1	tyrosine-type recombinase/integrase	-
OCF84_RS09070 (OCF84_09070)	2029686..2030228	+	543	WP_257748657.1	nucleotidyltransferase domain-containing protein	-
OCF84_RS09075 (OCF84_09075)	2030406..2031329	+	924	WP_282895401.1	IS5 family transposase	-
OCF84_RS09080 (OCF84_09080)	2031578..2032366	+	789	WP_257749919.1	type IV toxin-antitoxin system AbiEi family antitoxin	Antitoxin
OCF84_RS09085 (OCF84_09085)	2032359..2033294	+	936	WP_257749920.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
OCF84_RS09090 (OCF84_09090)	2033545..2034198	+	654	WP_257749921.1	tyrosine-type recombinase/integrase	-
OCF84_RS09095 (OCF84_09095)	2034276..2034440	-	165	WP_257749922.1	hypothetical protein	-
OCF84_RS09100 (OCF84_09100)	2034462..2034830	-	369	WP_257749923.1	zeta toxin family protein	-
OCF84_RS09105 (OCF84_09105)	2034894..2036077	+	1184	WP_257749930.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	2030406..2036077	5671

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (13-266)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-97)

Sequences

Toxin

Protein

• Length: 312 a.a.
• Molecular weight: 35358.18 Da
• Isoelectric Point: 7.0665

>T259921 WP_257749920.1 NZ_CP106874:2032359-2033294 [Shewanella xiamenensis]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAQINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLNELLLTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSIAALPAVRWKLLNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Nucleotide

• Length: 936 bp

Antitoxin

Protein

• Length: 263 a.a.
• Molecular weight: 29868.02 Da
• Isoelectric Point: 9.6662

>AT259921 WP_257749919.1 NZ_CP106874:2031578-2032366 [Shewanella xiamenensis]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPKSTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTEENQYE

Nucleotide

• Length: 789 bp