Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rnlAB/RnlA-RnlB
Location 22627..24064 Replicon chromosome
Accession NZ_CP106874
Organism Shewanella xiamenensis strain FH-1

Toxin (Protein)


Gene name rnlA Uniprot ID -
Locus tag OCF84_RS00110 Protein ID WP_129979812.1
Coordinates 22627..23697 (+) Length 357 a.a.

Antitoxin (Protein)


Gene name rnlB Uniprot ID -
Locus tag OCF84_RS00115 Protein ID WP_129979813.1
Coordinates 23699..24064 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCF84_RS00085 (OCF84_00085) 17831..18865 + 1035 WP_014611891.1 RhuM family protein -
OCF84_RS00090 (OCF84_00090) 18923..19600 - 678 WP_115164832.1 conjugative transfer protein MobI(A/C) -
OCF84_RS00095 (OCF84_00095) 20133..20333 + 201 WP_014611893.1 helix-turn-helix domain-containing protein -
OCF84_RS00100 (OCF84_00100) 20346..22022 + 1677 WP_257749017.1 DUF927 domain-containing protein -
OCF84_RS00105 (OCF84_00105) 22084..22428 + 345 WP_000136520.1 helix-turn-helix domain-containing protein -
OCF84_RS00110 (OCF84_00110) 22627..23697 + 1071 WP_129979812.1 type II toxin-antitoxin system RnlA family toxin Toxin
OCF84_RS00115 (OCF84_00115) 23699..24064 + 366 WP_129979813.1 type II toxin-antitoxin system RnlB family antitoxin Antitoxin
OCF84_RS00120 (OCF84_00120) 24061..25230 - 1170 WP_142739539.1 site-specific integrase -
OCF84_RS00125 (OCF84_00125) 25394..26755 - 1362 WP_188872118.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
OCF84_RS00130 (OCF84_00130) 26860..28485 - 1626 WP_037429332.1 membrane protein insertase YidC -
OCF84_RS00135 (OCF84_00135) 28489..28743 - 255 WP_037413461.1 membrane protein insertion efficiency factor YidD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Bacterial toxin, RNase RnlA/LsoA, N-terminal

(5-87)

Antitoxin

Antitoxin RnlB/LsoB

(15-111)


Sequences

Toxin        


Download         Length: 357 a.a.        Molecular weight: 40052.85 Da        Isoelectric Point: 6.2327

>T259920 WP_129979812.1 NZ_CP106874:22627-23697 [Shewanella xiamenensis]
VERSYKNLNLDRAAIKNLVESFATEHQFTIKSISAIPGTQKGTRIVFGRTGNKFATVNVFFNKDGTSTIQYLTGANHDIG
KLMTDHLYGSINPAEFEQVNMVLEGFTESAILPVLEFAAEESHIKVVVHAQDEHKTVWKIRSEEYQDELTVTLHIRTDKL
QIQGRPLSCYRVFIFNLSELLDLQGLEKVLIRQEDGNAEIVQQEVARSYLQSVLGESYERLHSNVEKLLISGLCVKLASP
NLPDYCMLLYPELRSIEGALKSKFMALGIEVGKDGFGDFFVKDQGVHVLNADCAALCANAEAAKIISEAYTFYNRERHGL
FHMEALVEASRMISNIAHLMTKSTQAWDLIKKLYSI

Download         Length: 1071 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13692.44 Da        Isoelectric Point: 3.9837

>AT259920 WP_129979813.1 NZ_CP106874:23699-24064 [Shewanella xiamenensis]
MFNIRRLSLDLNSIAIVTAIGYENPLSSLSEIEHELTCLLGQELNGEVIFDLVCSNGLEWNRFLSLQVKNGSFDYNSVSI
LDKTDFISQLFDEQAYFLSNNLHYLQDSVLTSDEIPRVIGV

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References