259909

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Xre-MNT/HTH_26(antitoxin)
Location 69086..70194 Replicon plasmid pFN9B
Accession NZ_CP106864
Organism Lysinibacillus capsici strain FN9

Toxin (Protein)


Gene name MNTss Uniprot ID A0A0M4MHJ8
Locus tag OCI51_RS26145 Protein ID WP_002303392.1
Coordinates 69325..70194 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name Xress Uniprot ID B9DSK1
Locus tag OCI51_RS26140 Protein ID WP_002303393.1
Coordinates 69086..69310 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCI51_RS26120 (OCI51_26120) 64087..64650 + 564 Protein_54 recombinase zinc beta ribbon domain-containing protein -
OCI51_RS26125 (OCI51_26125) 65093..66577 + 1485 WP_002294513.1 ABC-F type ribosomal protection protein Lsa(E) -
OCI51_RS26130 (OCI51_26130) 66631..67434 + 804 WP_002294514.1 lincosamide nucleotidyltransferase Lnu(B) -
OCI51_RS26135 (OCI51_26135) 68122..68943 + 822 Protein_57 recombinase family protein -
OCI51_RS26140 (OCI51_26140) 69086..69310 + 225 WP_002303393.1 helix-turn-helix transcriptional regulator Antitoxin
OCI51_RS26145 (OCI51_26145) 69325..70194 + 870 WP_002303392.1 nucleotidyltransferase domain-containing protein Toxin
OCI51_RS26150 (OCI51_26150) 70175..70909 + 735 WP_000662263.1 class I SAM-dependent methyltransferase -
OCI51_RS26155 (OCI51_26155) 70942..71805 + 864 WP_002294505.1 aminoglycoside nucleotidyltransferase ANT(6)-Ia -
OCI51_RS26160 (OCI51_26160) 71849..72376 + 528 WP_002294507.1 phosphoribosyltransferase family protein -
OCI51_RS26165 (OCI51_26165) 72508..73317 + 810 WP_002294509.1 ANT(9) family aminoglycoside nucleotidyltransferase Spw -
OCI51_RS26170 (OCI51_26170) 73490..73843 + 354 WP_263082621.1 DUF4440 domain-containing protein -
OCI51_RS26175 (OCI51_26175) 73998..74519 + 522 WP_263082622.1 GrpB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polymerase, nucleotidyl transferase domain

(12-111)

Antitoxin

Cro/C1-type helix-turn-helix domain

(4-57)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32807.38 Da        Isoelectric Point: 4.7269

>T259909 WP_002303392.1 NZ_CP106864:69325-70194 [Lysinibacillus capsici]
MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIYYNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDW
VNGGGWLVINGCHVDLILRDIKRVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYCINEKKAIKLLETFEYKPEKYAE
RVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEESSDERKQI

Download         Length: 870 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8351.65 Da        Isoelectric Point: 4.5357

>AT259909 WP_002303393.1 NZ_CP106864:69086-69310 [Lysinibacillus capsici]
MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKFVQAFILPDGDEIKISNE

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M4MHJ8

Antitoxin

Source ID Structure
AlphaFold DB A0A1M5SHM7

References