259908

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3294901..3296621 Replicon chromosome
Accession NZ_CP106852
Organism Edwardsiella ictaluri strain E9-302

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag N8I67_RS15545 Protein ID WP_198077154.1
Coordinates 3295965..3296621 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag N8I67_RS15540 Protein ID WP_012849888.1
Coordinates 3294901..3295968 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8I67_RS15525 (N8I67_15525) 3290141..3290695 + 555 WP_049640356.1 hypothetical protein -
N8I67_RS15530 (N8I67_15530) 3290926..3291642 - 717 WP_198077153.1 SprT family zinc-dependent metalloprotease -
N8I67_RS15535 (N8I67_15535) 3291642..3294737 - 3096 WP_049640354.1 HsdR family type I site-specific deoxyribonuclease -
N8I67_RS15540 (N8I67_15540) 3294901..3295968 - 1068 WP_012849888.1 macro domain-containing protein Antitoxin
N8I67_RS15545 (N8I67_15545) 3295965..3296621 - 657 WP_198077154.1 DUF4433 domain-containing protein Toxin
N8I67_RS15550 (N8I67_15550) 3296634..3298028 - 1395 WP_232347307.1 restriction endonuclease subunit S -
N8I67_RS15555 (N8I67_15555) 3298022..3300460 - 2439 WP_198077155.1 type I restriction-modification system subunit M -
N8I67_RS15560 (N8I67_15560) 3300499..3300738 - 240 WP_015872655.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3288371..3302347 13976


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25210.74 Da        Isoelectric Point: 6.9049

>T259908 WP_198077154.1 NZ_CP106852:c3296621-3295965 [Edwardsiella ictaluri]
MAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSQVQAANWINIGNPELIGKRAGHPVPVGMGGTLHDYVPFYFTP
FSPMLMNIHSGRGGITQRPNEEIVILVSNLRNVAAQNIPFVFTDSHAYYNWVNYYTRLEDLNQIDWPILQARDFRRDPDD
PAKFERYQAEALIWKHCPITLLVGMICYNDGVRLQLEQWLSQRNLTMPVHARAGWYFS

Download         Length: 657 bp

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40713.02 Da        Isoelectric Point: 6.9067

>AT259908 WP_012849888.1 NZ_CP106852:c3295968-3294901 [Edwardsiella ictaluri]
MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYAHACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKKVRSIAIPPLGAGNGGLNWPDVRARIESTLGDLQDTEILIYEPTEKYQNVAKSS
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNSEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGQCQPTLDSVKEG
LHQWPAGEPWASRKIKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References