Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 3295282..3297002 | Replicon | chromosome |
Accession | NZ_CP106849 | ||
Organism | Edwardsiella ictaluri strain 669 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | N8I66_RS15550 | Protein ID | WP_198077154.1 |
Coordinates | 3296346..3297002 (-) | Length | 219 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | N8I66_RS15545 | Protein ID | WP_012849888.1 |
Coordinates | 3295282..3296349 (-) | Length | 356 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N8I66_RS15530 (N8I66_15530) | 3290522..3291076 | + | 555 | WP_049640356.1 | hypothetical protein | - |
N8I66_RS15535 (N8I66_15535) | 3291307..3292023 | - | 717 | WP_198077153.1 | SprT family zinc-dependent metalloprotease | - |
N8I66_RS15540 (N8I66_15540) | 3292023..3295118 | - | 3096 | WP_049640354.1 | HsdR family type I site-specific deoxyribonuclease | - |
N8I66_RS15545 (N8I66_15545) | 3295282..3296349 | - | 1068 | WP_012849888.1 | macro domain-containing protein | Antitoxin |
N8I66_RS15550 (N8I66_15550) | 3296346..3297002 | - | 657 | WP_198077154.1 | DUF4433 domain-containing protein | Toxin |
N8I66_RS15555 (N8I66_15555) | 3297015..3298409 | - | 1395 | WP_232347307.1 | restriction endonuclease subunit S | - |
N8I66_RS15560 (N8I66_15560) | 3298403..3300841 | - | 2439 | WP_198077155.1 | type I restriction-modification system subunit M | - |
N8I66_RS15565 (N8I66_15565) | 3300880..3301119 | - | 240 | WP_015872655.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 3288752..3302728 | 13976 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25210.74 Da Isoelectric Point: 6.9049
>T259900 WP_198077154.1 NZ_CP106849:c3297002-3296346 [Edwardsiella ictaluri]
MAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSQVQAANWINIGNPELIGKRAGHPVPVGMGGTLHDYVPFYFTP
FSPMLMNIHSGRGGITQRPNEEIVILVSNLRNVAAQNIPFVFTDSHAYYNWVNYYTRLEDLNQIDWPILQARDFRRDPDD
PAKFERYQAEALIWKHCPITLLVGMICYNDGVRLQLEQWLSQRNLTMPVHARAGWYFS
MAYDYSANLNPEKALIWRIVHRDNIPWILDNGLHCGNSQVQAANWINIGNPELIGKRAGHPVPVGMGGTLHDYVPFYFTP
FSPMLMNIHSGRGGITQRPNEEIVILVSNLRNVAAQNIPFVFTDSHAYYNWVNYYTRLEDLNQIDWPILQARDFRRDPDD
PAKFERYQAEALIWKHCPITLLVGMICYNDGVRLQLEQWLSQRNLTMPVHARAGWYFS
Download Length: 657 bp
Antitoxin
Download Length: 356 a.a. Molecular weight: 40713.02 Da Isoelectric Point: 6.9067
>AT259900 WP_012849888.1 NZ_CP106849:c3296349-3295282 [Edwardsiella ictaluri]
MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYAHACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKKVRSIAIPPLGAGNGGLNWPDVRARIESTLGDLQDTEILIYEPTEKYQNVAKSS
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNSEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGQCQPTLDSVKEG
LHQWPAGEPWASRKIKLFDDKNLQFAINRVMEFHC
MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYAHACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKKVRSIAIPPLGAGNGGLNWPDVRARIESTLGDLQDTEILIYEPTEKYQNVAKSS
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNSEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGQCQPTLDSVKEG
LHQWPAGEPWASRKIKLFDDKNLQFAINRVMEFHC
Download Length: 1068 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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