Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2332213..2333826 Replicon chromosome
Accession NZ_CP106841
Organism Paenalcaligenes faecalis strain YLCF04

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag N7U67_RS11050 Protein ID WP_269900686.1
Coordinates 2332213..2333562 (-) Length 450 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag N7U67_RS11055 Protein ID WP_269900687.1
Coordinates 2333566..2333826 (-) Length 87 a.a.

Genomic Context

N7U67_RS11065N7U67_RS11025N7U67_RS11030N7U67_RS11035N7U67_RS11040N7U67_RS11045N7U67_RS11050N7U67_RS11055N7U67_RS11060N7U67_RS11070N7U67_RS11075N7U67_RS11080
Location: 2334965..2336086 (1122 bp)
Type: Others
Protein ID: WP_269900689.1
Location: 2327712..2328113 (402 bp)
Type: Others
Protein ID: WP_269900682.1
Location: 2328116..2328823 (708 bp)
Type: Others
Protein ID: WP_269900683.1
Location: 2328813..2329643 (831 bp)
Type: Others
Protein ID: WP_269900684.1
Location: 2330072..2330320 (249 bp)
Type: Others
Protein ID: Protein_2153
Location: 2330350..2331726 (1377 bp)
Type: Others
Protein ID: WP_269900685.1
Location: 2332213..2333562 (1350 bp)
Type: Toxin
Protein ID: WP_269900686.1
Location: 2333566..2333826 (261 bp)
Type: Antitoxin
Protein ID: WP_269900687.1
Location: 2334339..2334776 (438 bp)
Type: Others
Protein ID: WP_269900688.1
Location: 2336102..2337070 (969 bp)
Type: Others
Protein ID: WP_269900690.1
Location: 2337166..2337654 (489 bp)
Type: Others
Protein ID: WP_269900691.1
Location: 2337654..2338202 (549 bp)
Type: Others
Protein ID: WP_269900692.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N7U67_RS110252327712..2328113-402WP_269900682.1hypothetical protein-
N7U67_RS110302328116..2328823-708WP_269900683.1hypothetical protein-
N7U67_RS110352328813..2329643-831WP_269900684.1hypothetical protein-
N7U67_RS110402330072..2330320-249Protein_2153transposase-
N7U67_RS110452330350..2331726-1377WP_269900685.1integrase family protein-
N7U67_RS110502332213..2333562-1350WP_269900686.1type II toxin-antitoxin system HipA family toxinToxin
N7U67_RS110552333566..2333826-261WP_269900687.1helix-turn-helix transcriptional regulatorAntitoxin
N7U67_RS110602334339..2334776-438WP_269900688.1hypothetical protein-
N7U67_RS110652334965..2336086+1122WP_269900689.1diguanylate cyclase-
N7U67_RS110702336102..2337070-969WP_269900690.1chemotaxis protein-
N7U67_RS110752337166..2337654-489WP_269900691.1hypothetical protein-
N7U67_RS110802337654..2338202-549WP_269900692.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(10-112)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-67)


Sequences

Toxin        


Download         Length: 450 a.a.        Molecular weight: 50043.20 Da        Isoelectric Point: 6.5764

>T259891 WP_269900686.1 NZ_CP106841:c2333562-2332213 [Paenalcaligenes faecalis]
MGRRSHTQTLYLWMNGYFVGTWSVRPYTGDILQYDEGWVVSEHGRPLSLSLPFTPGNPPHRGDAVRTYFENLLPDSEDIL
KRVARRFQASSTGAFALLAEIGRDCVGALQILPDNVPPEGVQEVSATPLTDAEVAQVLRNTLASVSLIQGSDDVDFRISI
AGAQEKTALSWLNGQWCLPHGATPTTHIFKLPLGLVGNLRFDMSDSVENEWLCSKILHAYGLPVASTQILEFEDMKVLAV
ERFDRMWWENEEGKRWLLRIPQEDMCQATGTPPYLKYESDGGPGVRTIMKLLATSRDPDRDRRTFFQAQVLFWMLSATDG
HAKNFSIFLRPEGTYELTPLYDVLSAYPVIGKGANQLSPFKAKLAMAVRSKNPHWVMRDILRRHWLAVGAEHGVVAPDGR
GAEAVLDDLVAKTPEVVRAVRALLPKRFPEHVADSILNGLQLAANKLTG

Download         Length: 1350 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9467.93 Da        Isoelectric Point: 10.3016

>AT259891 WP_269900687.1 NZ_CP106841:c2333826-2333566 [Paenalcaligenes faecalis]
MTDFTIRTADQLPLMLQAFRKQANLTQTDVAMRLGVTQQTLSALERNAKKVSAERLLELLSILGVELVLRQNSDAPSPKP
STGSGW

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References