Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4241423..4241591 Replicon chromosome
Accession NZ_CP106838
Organism Klebsiella michiganensis strain K5-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4241481..4241584 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4241423..4241591 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6B35_RS20210 (N6B35_20210) 4236550..4238610 + 2061 WP_033836507.1 oligopeptidase B -
N6B35_RS20215 (N6B35_20215) 4238617..4239276 - 660 WP_014229839.1 exodeoxyribonuclease X -
N6B35_RS20220 (N6B35_20220) 4239355..4239585 - 231 WP_004103351.1 DNA polymerase III subunit theta -
N6B35_RS20225 (N6B35_20225) 4239721..4240095 + 375 WP_014229838.1 CopC domain-containing protein YobA -
N6B35_RS20230 (N6B35_20230) 4240100..4240969 + 870 WP_047723551.1 copper homeostasis membrane protein CopD -
N6B35_RS20235 (N6B35_20235) 4240986..4241324 + 339 WP_004103344.1 YebY family protein -
- 4241423..4241591 - 169 - - Antitoxin
- 4241481..4241584 + 104 - - Toxin
N6B35_RS20240 (N6B35_20240) 4241709..4242668 - 960 WP_047723552.1 spore coat protein U domain-containing protein -
N6B35_RS20245 (N6B35_20245) 4242683..4245013 - 2331 WP_047723554.1 fimbria/pilus outer membrane usher protein -
N6B35_RS20250 (N6B35_20250) 4245016..4245780 - 765 WP_025106133.1 fimbria/pilus periplasmic chaperone -
N6B35_RS20255 (N6B35_20255) 4245799..4246317 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T259883 NZ_CP106838:4241481-4241584 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT259883 NZ_CP106838:c4241591-4241423 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References