259878

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 825829..826648 Replicon chromosome
Accession NZ_CP106838
Organism Klebsiella michiganensis strain K5-3

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag N6B35_RS03965 Protein ID WP_004110819.1
Coordinates 826391..826648 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag N6B35_RS03960 Protein ID WP_221691059.1
Coordinates 825829..826380 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6B35_RS03940 (N6B35_03940) 821199..822596 + 1398 WP_014228060.1 MFS transporter -
N6B35_RS03945 (N6B35_03945) 822718..824058 + 1341 WP_057173103.1 carbohydrate porin -
N6B35_RS03950 (N6B35_03950) 824183..824929 - 747 WP_014228056.1 class I SAM-dependent methyltransferase -
N6B35_RS03955 (N6B35_03955) 825353..825715 - 363 Protein_775 class I SAM-dependent methyltransferase -
N6B35_RS03960 (N6B35_03960) 825829..826380 - 552 WP_221691059.1 N-acetyltransferase Antitoxin
N6B35_RS03965 (N6B35_03965) 826391..826648 - 258 WP_004110819.1 YjhX family toxin Toxin
N6B35_RS03970 (N6B35_03970) 827324..828508 + 1185 WP_047724369.1 mannonate dehydratase -
N6B35_RS03975 (N6B35_03975) 828582..830057 + 1476 WP_080528514.1 fructuronate reductase -
N6B35_RS03980 (N6B35_03980) 830196..830972 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T259878 WP_004110819.1 NZ_CP106838:c826648-826391 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19992.88 Da        Isoelectric Point: 6.8217

>AT259878 WP_221691059.1 NZ_CP106838:c826380-825829 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYRGVGVGGGLIRHGIEQLKAMGSQMVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPAAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References