Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 38419..38931 Replicon chromosome
Accession NZ_CP106831
Organism Empedobacter falsenii strain YWS9-3_T

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OBA43_RS00185 Protein ID WP_284583521.1
Coordinates 38674..38931 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OBA43_RS00180 Protein ID WP_171622164.1
Coordinates 38419..38673 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OBA43_RS00165 (OBA43_00165) 34073..36409 + 2337 WP_284583519.1 DUF2357 domain-containing protein -
OBA43_RS00170 (OBA43_00170) 36625..36822 + 198 WP_284583520.1 hypothetical protein -
OBA43_RS00175 (OBA43_00175) 36900..37709 + 810 WP_225540620.1 GIY-YIG nuclease family protein -
OBA43_RS00180 (OBA43_00180) 38419..38673 + 255 WP_171622164.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OBA43_RS00185 (OBA43_00185) 38674..38931 + 258 WP_284583521.1 Txe/YoeB family addiction module toxin Toxin
OBA43_RS00190 (OBA43_00190) 40257..40964 + 708 WP_284583522.1 IS30 family transposase -
OBA43_RS00195 (OBA43_00195) 40981..41271 + 291 WP_284583523.1 IS30 family transposase -
OBA43_RS00200 (OBA43_00200) 41421..42074 + 654 WP_284583524.1 MarR family transcriptional regulator -
OBA43_RS00205 (OBA43_00205) 42088..42492 + 405 WP_225541518.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10588.20 Da        Isoelectric Point: 9.7901

>T259867 WP_284583521.1 NZ_CP106831:38674-38931 [Empedobacter falsenii]
MKYIFVDESWEDYLFWQKTDKKKVKRINDLLKDISRTPFTGIRKPEPLKHKYSGFWSRRIDDEHRLIYKYEDGQILIAKC
RFHYD

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9681.97 Da        Isoelectric Point: 4.6561

>AT259867 WP_171622164.1 NZ_CP106831:38419-38673 [Empedobacter falsenii]
MLIASVSDFRKDLKSYLDRVSKNFETLIINRGKDSGIVVMSLEEYNSLMATNYELSSRINESRLDSAIEKLKSNQSFEKE
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References