259832

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Txe-YefM
Location 2701031..2701563 Replicon chromosome
Accession NZ_CP106793
Organism Streptomyces sp. HUAS 13-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8I84_RS12610 Protein ID WP_263229609.1
Coordinates 2701031..2701294 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8I84_RS12615 Protein ID WP_263229610.1
Coordinates 2701291..2701563 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8I84_RS12595 (N8I84_12595) 2697223..2698836 + 1614 WP_263229607.1 MFS transporter -
N8I84_RS12600 (N8I84_12600) 2698959..2699414 + 456 WP_200417762.1 archease -
N8I84_RS12605 (N8I84_12605) 2699460..2700872 - 1413 WP_263229608.1 RtcB family protein -
N8I84_RS12610 (N8I84_12610) 2701031..2701294 - 264 WP_263229609.1 Txe/YoeB family addiction module toxin Toxin
N8I84_RS12615 (N8I84_12615) 2701291..2701563 - 273 WP_263229610.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N8I84_RS12620 (N8I84_12620) 2701945..2703126 - 1182 WP_263229611.1 acyltransferase -
N8I84_RS12625 (N8I84_12625) 2703372..2704367 - 996 WP_263229612.1 NADPH:quinone oxidoreductase family protein -
N8I84_RS12630 (N8I84_12630) 2704403..2705167 - 765 WP_263229613.1 SDR family oxidoreductase -
N8I84_RS12635 (N8I84_12635) 2705201..2705689 - 489 WP_263229614.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-71)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10480.82 Da        Isoelectric Point: 7.2010

>T259832 WP_263229609.1 NZ_CP106793:c2701294-2701031 [Streptomyces sp. HUAS 13-4]
VRDVNFDPGAWDDFQYWLETDRKMVRRVVRLIGEIQRDPFNGIGKPEPLKGDLSGYWSRRVDDEHRLVYRVDDKEVKILK
ARYHYAD

Download         Length: 264 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10095.37 Da        Isoelectric Point: 5.1408

>AT259832 WP_263229610.1 NZ_CP106793:c2701563-2701291 [Streptomyces sp. HUAS 13-4]
MAFTASEARKELFPLIKKVNDDHAPVRIHSKHGDAILMSAEDYDAWQETIYLLRSPANARRLMEAVARDRAGQTGITKSL
DDLQELAGEE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References