Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2124620..2124765 Replicon chromosome
Accession NZ_CP106786
Organism Klebsiella pneumoniae strain KP1161

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2124656..2124758 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2124620..2124765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9H76_RS10410 (N9H76_10410) 2119750..2121810 + 2061 WP_004151449.1 oligopeptidase B -
N9H76_RS10415 (N9H76_10415) 2121814..2122473 - 660 WP_002911407.1 exodeoxyribonuclease X -
N9H76_RS10420 (N9H76_10420) 2122552..2122782 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N9H76_RS10425 (N9H76_10425) 2122895..2123269 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N9H76_RS10430 (N9H76_10430) 2123273..2124142 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
N9H76_RS10435 (N9H76_10435) 2124159..2124497 + 339 WP_002911404.1 YebY family protein -
- 2124620..2124765 - 146 - - Antitoxin
- 2124656..2124758 + 103 - - Toxin
N9H76_RS10440 (N9H76_10440) 2125134..2125277 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N9H76_RS10445 (N9H76_10445) 2125382..2126350 - 969 WP_004151446.1 VirK/YbjX family protein -
N9H76_RS10450 (N9H76_10450) 2126507..2127160 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
N9H76_RS10455 (N9H76_10455) 2127157..2127348 - 192 WP_002911395.1 YebW family protein -
N9H76_RS10460 (N9H76_10460) 2127446..2127685 - 240 WP_002911393.1 YebV family protein -
N9H76_RS10465 (N9H76_10465) 2127801..2129234 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T259818 NZ_CP106786:2124656-2124758 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT259818 NZ_CP106786:c2124765-2124620 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References