Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4762082..4763490 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N9L84_RS21735 Protein ID WP_263150773.1
Coordinates 4762921..4763490 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag N9L84_RS21730 Protein ID WP_263150771.1
Coordinates 4762082..4762924 (-) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS21705 (N9L84_21705) 4757502..4758449 + 948 WP_263150768.1 bile acid:sodium symporter family protein -
N9L84_RS21710 (N9L84_21710) 4758597..4758911 + 315 WP_263150769.1 quaternary ammonium compound efflux SMR transporter SugE -
N9L84_RS21715 (N9L84_21715) 4758975..4760849 - 1875 WP_173171964.1 MFS transporter -
N9L84_RS21720 (N9L84_21720) 4761002..4761331 - 330 WP_213625826.1 AzlD domain-containing protein -
N9L84_RS21725 (N9L84_21725) 4761331..4762044 - 714 WP_263150770.1 AzlC family ABC transporter permease -
N9L84_RS21730 (N9L84_21730) 4762082..4762924 - 843 WP_263150771.1 AraC family transcriptional regulator Antitoxin
N9L84_RS21735 (N9L84_21735) 4762921..4763490 - 570 WP_263150773.1 GNAT family protein Toxin
N9L84_RS21740 (N9L84_21740) 4763742..4767218 + 3477 WP_263150774.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(17-149)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21249.20 Da        Isoelectric Point: 6.8864

>T259809 WP_263150773.1 NZ_CP106785:c4763490-4762921 [Pseudomonas tohonis]
MFNPQPVILQRGALRLEPLGEADVTELSALAEANRDELVYMSGPLRPDWYRQGLAEQREGQAVVFAIRLGDRLVGTSRFA
DFMPALPAVEIGWTWLARSEHASGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQKAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHEWPAVKQALEASFGQ

Download         Length: 570 bp

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31226.59 Da        Isoelectric Point: 9.4278

>AT259809 WP_263150771.1 NZ_CP106785:c4762924-4762082 [Pseudomonas tohonis]
MSAGGERTRFWQASALGGVELLHARYIEQRFSPHVHEGYVFTVLESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTEVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHRLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGPEPHAVALAREMLAARLASPPSLEELAALVGLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLREGCAPL
PVAMQLGFADQSHLTRQFKQAYGVGPGEYRSACARSFKTG

Download         Length: 843 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References