Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4420419..4421016 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N9L84_RS20100 Protein ID WP_263150462.1
Coordinates 4420419..4420727 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N9L84_RS20105 Protein ID WP_173177962.1
Coordinates 4420720..4421016 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS20085 (N9L84_20085) 4416431..4418068 - 1638 WP_263150457.1 AMP-binding protein -
N9L84_RS20090 (N9L84_20090) 4418181..4419011 - 831 WP_263150458.1 amidohydrolase family protein -
N9L84_RS20095 (N9L84_20095) 4419079..4420218 - 1140 WP_263150460.1 acyl-CoA dehydrogenase family protein -
N9L84_RS20100 (N9L84_20100) 4420419..4420727 + 309 WP_263150462.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N9L84_RS20105 (N9L84_20105) 4420720..4421016 + 297 WP_173177962.1 putative addiction module antidote protein Antitoxin
N9L84_RS20110 (N9L84_20110) 4421107..4422393 - 1287 WP_263150463.1 dicarboxylate/amino acid:cation symporter -
N9L84_RS20115 (N9L84_20115) 4422717..4423715 + 999 WP_263150464.1 AraC family transcriptional regulator -
N9L84_RS20120 (N9L84_20120) 4423773..4424090 - 318 WP_263150465.1 putative quinol monooxygenase -
N9L84_RS20125 (N9L84_20125) 4424253..4424843 + 591 WP_213625612.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-90)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11386.11 Da        Isoelectric Point: 10.8297

>T259808 WP_263150462.1 NZ_CP106785:4420419-4420727 [Pseudomonas tohonis]
MIKVLQSRAFATWLNHLSDGKARARILARIDRMADGHLGDVAPIGEGLSEARLHFGPGYRLYFLQRGRFLIVLLCGGDKG
SQGRDIGHARRIAAAWKEQHHD

Download         Length: 309 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10732.01 Da        Isoelectric Point: 4.6533

>AT259808 WP_173177962.1 NZ_CP106785:4420720-4421016 [Pseudomonas tohonis]
MTEDFSRWDSADYLRSEEDMANYLDACIEEAGDDPAFIAKALGTLARAKGMTQVARDTGLSRESLYRALSGEGNPEFGTI
LKVLRALGLQLHASPARH

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References