Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3931884..3932517 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N9L84_RS17775 Protein ID WP_263150043.1
Coordinates 3931884..3932255 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N9L84_RS17780 Protein ID WP_263150045.1
Coordinates 3932281..3932517 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS17740 (N9L84_17740) 3927021..3927293 + 273 WP_021217973.1 DUF2282 domain-containing protein -
N9L84_RS17745 (N9L84_17745) 3927310..3928149 + 840 WP_263150034.1 DUF692 domain-containing protein -
N9L84_RS17750 (N9L84_17750) 3928146..3928931 + 786 WP_263150035.1 DNA-binding domain-containing protein -
N9L84_RS17755 (N9L84_17755) 3928945..3929409 + 465 WP_263150037.1 DoxX family protein -
N9L84_RS17760 (N9L84_17760) 3929417..3930013 - 597 WP_263150039.1 chalcone isomerase family protein -
N9L84_RS17765 (N9L84_17765) 3930087..3930983 - 897 WP_263150040.1 alpha/beta hydrolase -
N9L84_RS17770 (N9L84_17770) 3931108..3931875 + 768 WP_263150041.1 DUF2092 domain-containing protein -
N9L84_RS17775 (N9L84_17775) 3931884..3932255 - 372 WP_263150043.1 PIN domain-containing protein Toxin
N9L84_RS17780 (N9L84_17780) 3932281..3932517 - 237 WP_263150045.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N9L84_RS17785 (N9L84_17785) 3932657..3933289 + 633 WP_263150046.1 hypothetical protein -
N9L84_RS17790 (N9L84_17790) 3933462..3934376 - 915 WP_263150047.1 LysR family transcriptional regulator -
N9L84_RS17795 (N9L84_17795) 3934535..3935872 + 1338 WP_263150049.1 nucleobase:cation symporter-2 family protein -
N9L84_RS17800 (N9L84_17800) 3935912..3936418 + 507 WP_263150050.1 nucleoside deaminase -
N9L84_RS17805 (N9L84_17805) 3936415..3936771 + 357 WP_263150052.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-105)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13568.81 Da        Isoelectric Point: 7.1892

>T259807 WP_263150043.1 NZ_CP106785:c3932255-3931884 [Pseudomonas tohonis]
VLLYLLSADPAKADAAEALLAKRPTISVQVLNEVASVCSRKLRMSWDEIGRFLELVQGFCRVVPVTLEIHRQARELAERY
RLSFYDACIAAAALVAGCSTLHSEDMHSGLLLDGRLRVLNPFG

Download         Length: 372 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8785.90 Da        Isoelectric Point: 4.6838

>AT259807 WP_263150045.1 NZ_CP106785:c3932517-3932281 [Pseudomonas tohonis]
MQVAKWGNSLAVRIPASVVEALELKEGDDIEILIEGDRTFAISKKPDDEGRLARLRAFRGKLPADFRFNRDEDAGRED

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References