Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 3650576..3651251 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag N9L84_RS16575 Protein ID WP_263149783.1
Coordinates 3650576..3650761 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag N9L84_RS16580 Protein ID WP_263149784.1
Coordinates 3650808..3651251 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS16550 (N9L84_16550) 3645611..3646309 - 699 WP_263149776.1 phytanoyl-CoA dioxygenase family protein -
N9L84_RS16555 (N9L84_16555) 3646306..3646863 - 558 WP_263149778.1 D-alanyl-D-alanine carboxypeptidase family protein -
N9L84_RS16560 (N9L84_16560) 3647665..3648216 - 552 WP_263149779.1 hypothetical protein -
N9L84_RS16565 (N9L84_16565) 3648508..3649575 - 1068 WP_263149780.1 hypothetical protein -
N9L84_RS16570 (N9L84_16570) 3649793..3650149 - 357 WP_263149781.1 hypothetical protein -
N9L84_RS16575 (N9L84_16575) 3650576..3650761 + 186 WP_263149783.1 type II toxin-antitoxin system HicA family toxin Toxin
N9L84_RS16580 (N9L84_16580) 3650808..3651251 + 444 WP_263149784.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
N9L84_RS16585 (N9L84_16585) 3651485..3652135 + 651 WP_263149785.1 hypothetical protein -
N9L84_RS16590 (N9L84_16590) 3652163..3652720 + 558 WP_263149786.1 hypothetical protein -
N9L84_RS16595 (N9L84_16595) 3653006..3655081 - 2076 WP_263149787.1 phospholipase C, phosphocholine-specific -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(5-59)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 6881.04 Da        Isoelectric Point: 10.8832

>T259806 WP_263149783.1 NZ_CP106785:3650576-3650761 [Pseudomonas tohonis]
MKHSEFRRWLKAQGVIFEAAKGSHFKITAPNGKTTIFADHGAKEMKEPTRKAIIKQLGLTE

Download         Length: 186 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16141.54 Da        Isoelectric Point: 4.6651

>AT259806 WP_263149784.1 NZ_CP106785:3650808-3651251 [Pseudomonas tohonis]
MYDYAIRLEADDTPGLAVFCRDLPELNSYGDDVAHALAEAVDAIESTLSLYVDQRRTIPTASPAEAGEHVIRLPAVTVAK
IYLWNAMMEQGLRKADLCRLLGVAPMQVDRLVDFLHTSKMEAVETALAKLGKRLAVSIEAGEWPRSA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References