Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2539858..2541111 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N9L84_RS11655 Protein ID WP_263153897.1
Coordinates 2540527..2541111 (+) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N9L84_RS11650 Protein ID WP_263153896.1
Coordinates 2539858..2540415 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS11630 (N9L84_11630) 2535404..2536015 + 612 WP_263153891.1 LysE family translocator -
N9L84_RS11635 (N9L84_11635) 2536018..2538105 - 2088 WP_263153892.1 PAS domain S-box protein -
N9L84_RS11640 (N9L84_11640) 2538290..2539039 + 750 WP_263153893.1 NAD-dependent deacylase -
N9L84_RS11645 (N9L84_11645) 2539066..2539581 - 516 WP_263153895.1 thioredoxin family protein -
N9L84_RS11650 (N9L84_11650) 2539858..2540415 + 558 WP_263153896.1 helix-turn-helix transcriptional regulator Antitoxin
N9L84_RS11655 (N9L84_11655) 2540527..2541111 + 585 WP_263153897.1 HD domain-containing protein Toxin
N9L84_RS11660 (N9L84_11660) 2541321..2541704 + 384 WP_263153898.1 cytochrome c -
N9L84_RS11665 (N9L84_11665) 2541730..2541870 - 141 WP_173174516.1 DUF2256 domain-containing protein -
N9L84_RS11670 (N9L84_11670) 2541867..2543408 - 1542 WP_263153899.1 cryptochrome/photolyase family protein -
N9L84_RS11675 (N9L84_11675) 2543405..2543710 - 306 WP_263153900.1 DUF6482 family protein -
N9L84_RS11680 (N9L84_11680) 2543741..2544277 - 537 WP_263153901.1 DUF3833 domain-containing protein -
N9L84_RS11685 (N9L84_11685) 2544289..2544840 - 552 WP_263153902.1 chalcone isomerase family protein -
N9L84_RS11690 (N9L84_11690) 2545069..2546025 + 957 WP_173174505.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(7-189)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-67)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21603.23 Da        Isoelectric Point: 4.6874

>T259805 WP_263153897.1 NZ_CP106785:2540527-2541111 [Pseudomonas tohonis]
MNIDTIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAQEREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQASAAR

Download         Length: 585 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20280.42 Da        Isoelectric Point: 8.8016

>AT259805 WP_263153896.1 NZ_CP106785:2539858-2540415 [Pseudomonas tohonis]
MHDSLPKPVSLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFSVPLSELMGRSLWRYATPEIVRQEAALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References