Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1809799..1810388 Replicon chromosome
Accession NZ_CP106785
Organism Pseudomonas tohonis strain G5.110

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N9L84_RS08430 Protein ID WP_263153316.1
Coordinates 1809799..1810098 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N9L84_RS08435 Protein ID WP_263153318.1
Coordinates 1810095..1810388 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N9L84_RS08400 (N9L84_08400) 1804967..1806502 + 1536 WP_263153313.1 DHA2 family efflux MFS transporter permease subunit -
N9L84_RS08410 (N9L84_08410) 1806905..1807126 - 222 WP_021219560.1 YgdI/YgdR family lipoprotein -
N9L84_RS08415 (N9L84_08415) 1807211..1807798 - 588 WP_263153314.1 molybdenum cofactor guanylyltransferase MobA -
N9L84_RS08420 (N9L84_08420) 1807871..1808410 + 540 WP_173173724.1 molybdenum cofactor biosynthesis protein B -
N9L84_RS08425 (N9L84_08425) 1808407..1809621 + 1215 WP_213628903.1 molybdopterin molybdotransferase MoeA -
N9L84_RS08430 (N9L84_08430) 1809799..1810098 + 300 WP_263153316.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N9L84_RS08435 (N9L84_08435) 1810095..1810388 + 294 WP_263153318.1 putative addiction module antidote protein Antitoxin
N9L84_RS08440 (N9L84_08440) 1810389..1811411 - 1023 WP_263153319.1 AraC family transcriptional regulator -
N9L84_RS08445 (N9L84_08445) 1811544..1813139 + 1596 WP_263153320.1 FAD-binding oxidoreductase -
N9L84_RS08450 (N9L84_08450) 1813142..1814719 + 1578 WP_263153321.1 glycerol-3-phosphate dehydrogenase/oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11092.73 Da        Isoelectric Point: 11.1304

>T259804 WP_263153316.1 NZ_CP106785:1809799-1810098 [Pseudomonas tohonis]
MITIRQTATFAAWERKLKDRKARAAIAARIFRLANGLPGDVAPVGQGVSEMRINYGPGYRVYFQQRGNELVILLCGGDKS
SQGRDIEQARRLAAEWRSQ

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10412.90 Da        Isoelectric Point: 4.4488

>AT259804 WP_263153318.1 NZ_CP106785:1810095-1810388 [Pseudomonas tohonis]
MMEELYDYDPAEALGSPEAIAVFVADALETGDAAYIAKAMGVVARAKGMTELARETGLSREQLYRSFSEQGNPTLRTMLA
VMRALGLDMTAKPHSAA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References