Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2340931..2342279 Replicon chromosome
Accession NC_016816
Organism Pantoea ananatis LMG 5342

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag PANA5342_RS33580 Protein ID WP_015700267.1
Coordinates 2341170..2342279 (+) Length 370 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag PANA5342_RS33575 Protein ID WP_013025828.1
Coordinates 2340931..2341170 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PANA5342_RS33560 2336523..2337911 + 1389 WP_014605798.1 MFS transporter -
PANA5342_RS33565 2337934..2340309 + 2376 WP_015700265.1 glycoside hydrolase family 3 C-terminal domain-containing protein -
PANA5342_RS33570 2340373..2340816 - 444 WP_015700266.1 GNAT family N-acetyltransferase -
PANA5342_RS33575 2340931..2341170 + 240 WP_013025828.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
PANA5342_RS33580 2341170..2342279 + 1110 WP_015700267.1 HipA domain-containing protein Toxin
PANA5342_RS33585 2342325..2342741 - 417 WP_013025826.1 GFA family protein -
PANA5342_RS33590 2343192..2345060 - 1869 WP_013025825.1 low affinity potassium transporter Kup -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(6-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-63)


Sequences

Toxin        


Download         Length: 370 a.a.        Molecular weight: 40829.12 Da        Isoelectric Point: 7.4551

>T25978 WP_015700267.1 NC_016816:2341170-2342279 [Pantoea ananatis LMG 5342]
MAKLIAWINGERTGTLTLHHNGALHFQYDANWLQHPLARPLSLSLPLQRAAMHSEKVVHFFENLLYPSALIEKDFYPTHP
IKSCEVFAALQKVGHTLPGALSLLPAKRQPVAPDQATHSVFSPADEAQQFDIDNAYLCLSLARELTIPVPDAVLVHENGI
RKLRTERYDRRWRHDGQHLYHLPEEDVCQALGVPLSGRDEQQGGPGIDDIMALLMGSSSAMKDREDLMRCLVFQWLTGIT
RVNAKHLSLLIARGGSFRLAPFKHLLSACPGLSLRTTDRRDFQLGIGLTGPEGKQHHIDAIGPAHFLALAGSVGFSQAAM
RQILAAFVPGLPAAIVKVRDSLPDDYPLTLADAVFSHAMMMLERVRQAI

Download         Length: 1110 bp

>T25978 NC_016816:2341170-2342279 [Pantoea ananatis LMG 5342]
ATGGCAAAGCTCATTGCCTGGATAAACGGCGAGCGTACGGGAACGCTGACGCTGCATCACAACGGCGCGCTGCATTTCCA
GTATGACGCCAACTGGCTTCAGCATCCGCTTGCCAGACCTCTCTCGCTTTCGTTGCCCTTACAGCGCGCCGCGATGCATT
CTGAGAAAGTCGTGCACTTTTTCGAAAACCTTCTCTATCCCAGCGCGTTGATCGAAAAGGATTTTTACCCGACTCACCCG
ATAAAATCCTGTGAGGTGTTTGCTGCATTGCAGAAAGTGGGACACACATTGCCCGGGGCGCTCAGTCTGCTGCCGGCAAA
GCGGCAGCCCGTCGCGCCGGACCAGGCAACGCACAGCGTCTTCAGCCCCGCCGATGAGGCACAGCAGTTCGATATCGATA
ATGCGTATCTGTGTCTGTCCCTGGCCCGGGAGCTAACTATCCCGGTGCCGGATGCCGTGTTAGTTCATGAGAACGGCATC
CGTAAATTGAGAACAGAACGATACGATCGCCGTTGGCGTCACGACGGACAACACCTTTATCATCTTCCTGAAGAAGACGT
GTGTCAGGCGCTCGGCGTGCCGCTCTCTGGCCGCGATGAGCAGCAGGGCGGTCCGGGAATTGATGACATCATGGCCTTGC
TGATGGGCTCAAGCTCCGCCATGAAAGACCGTGAGGATCTGATGCGCTGTCTGGTATTTCAGTGGCTGACGGGCATCACG
CGCGTCAACGCTAAACATCTCTCGCTGCTGATTGCTCGCGGTGGCAGCTTCCGGCTCGCGCCTTTTAAGCATCTCCTTTC
CGCCTGCCCGGGCCTTTCTCTGCGCACAACAGACAGACGAGATTTCCAGCTGGGGATAGGCCTGACAGGCCCTGAGGGCA
AACAGCATCACATTGACGCGATTGGGCCCGCGCATTTTCTTGCCCTTGCGGGGAGCGTGGGGTTCAGTCAGGCAGCGATG
CGGCAGATACTCGCGGCCTTTGTTCCGGGCTTGCCTGCCGCGATTGTTAAGGTGCGGGACAGCCTGCCCGATGATTATCC
CCTGACGCTCGCCGATGCGGTTTTCAGCCACGCAATGATGATGCTGGAAAGGGTGCGCCAGGCGATCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8746.94 Da        Isoelectric Point: 7.2012

>AT25978 WP_013025828.1 NC_016816:2340931-2341170 [Pantoea ananatis LMG 5342]
MIYSPRQLANQVRLLRQQNGWTQVELAKKVGLKQATLSHFENAPDTTSLATLFKILQALDLALSLHENSASSAPAEDAW

Download         Length: 240 bp

>AT25978 NC_016816:2340931-2341170 [Pantoea ananatis LMG 5342]
ATGATTTACAGTCCCCGCCAGTTGGCGAATCAGGTCAGGCTATTGCGGCAGCAAAACGGCTGGACCCAGGTCGAACTGGC
GAAAAAAGTGGGCCTGAAACAGGCAACCCTGTCTCACTTCGAAAATGCCCCGGATACAACCTCACTGGCAACGTTGTTCA
AAATCTTACAGGCGCTCGATCTTGCTCTGTCGCTTCATGAAAACAGCGCATCCTCAGCCCCGGCTGAGGATGCCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References