Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014247..2014392 Replicon chromosome
Accession NZ_CP106760
Organism Klebsiella pneumoniae strain KP0937

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014283..2014385 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014247..2014392 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8627_RS09885 (N8627_09885) 2009377..2011437 + 2061 WP_004151449.1 oligopeptidase B -
N8627_RS09890 (N8627_09890) 2011441..2012100 - 660 WP_002911407.1 exodeoxyribonuclease X -
N8627_RS09895 (N8627_09895) 2012179..2012409 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N8627_RS09900 (N8627_09900) 2012522..2012896 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N8627_RS09905 (N8627_09905) 2012900..2013769 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
N8627_RS09910 (N8627_09910) 2013786..2014124 + 339 WP_002911404.1 YebY family protein -
- 2014247..2014392 - 146 - - Antitoxin
- 2014283..2014385 + 103 - - Toxin
N8627_RS09915 (N8627_09915) 2014760..2014903 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N8627_RS09920 (N8627_09920) 2015008..2015976 - 969 WP_004151446.1 VirK/YbjX family protein -
N8627_RS09925 (N8627_09925) 2016133..2016786 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
N8627_RS09930 (N8627_09930) 2016783..2016974 - 192 WP_002911395.1 YebW family protein -
N8627_RS09935 (N8627_09935) 2017072..2017311 - 240 WP_002911393.1 YebV family protein -
N8627_RS09940 (N8627_09940) 2017427..2018860 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T259752 NZ_CP106760:2014283-2014385 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT259752 NZ_CP106760:c2014392-2014247 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References