Detailed information of TA system TA259707

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicB(antitoxin)
• Location: 4566651..4567288
• Replicon: chromosome
• Accession: NZ_CP106754
• Organism: Kosakonia sp. ML.JS2a

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: N7922_RS21560
• Protein ID: WP_263098199.1
• Coordinates: 4566651..4566821 (+)
• Length: 57 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: -
• Locus tag: N7922_RS21565
• Protein ID: WP_263098200.1
• Coordinates: 4566851..4567288 (+)
• Length: 146 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (16-55)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (4-82)

Sequences

Toxin

Protein

• Length: 57 a.a.
• Molecular weight: 6392.65 Da
• Isoelectric Point: 11.0962

>T259707 WP_263098199.1 NZ_CP106754:4566651-4566821 [Kosakonia sp. ML.JS2a]
MKYSEFRKWLLLIKAPGGGSHFKVKLNGRASVFPFHGSKEIPEPLRKKILKDLGLQ

Nucleotide

• Length: 171 bp

Antitoxin

Protein

• Length: 146 a.a.
• Molecular weight: 15926.27 Da
• Isoelectric Point: 4.7503

>AT259707 WP_263098200.1 NZ_CP106754:4566851-4567288 [Kosakonia sp. ML.JS2a]
MFNYPVSVEQDDVTGQFVVSCRDLPLMNSVGDTLDDALLQSVDAMVVAIAIEVDERRPIPQASAALPGEYVVSLPVLVAM
KAALHNAMIETGTRKAELARKLGQKGPQIDRLLDVEHSSKVETVELALHQLNRQIDLTITQQHRT

Nucleotide

• Length: 438 bp