Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3421828..3422744 Replicon chromosome
Accession NZ_CP106754
Organism Kosakonia sp. ML.JS2a

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N7922_RS16265 Protein ID WP_263097309.1
Coordinates 3422268..3422744 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag N7922_RS16260 Protein ID WP_088237186.1
Coordinates 3421828..3422271 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7922_RS16235 (N7922_16235) 3416864..3418630 + 1767 WP_263097305.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD -
N7922_RS16240 (N7922_16240) 3418631..3420352 + 1722 WP_263097306.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
N7922_RS16245 (N7922_16245) 3420460..3421161 + 702 WP_263097308.1 leucyl/phenylalanyl-tRNA--protein transferase -
N7922_RS16250 (N7922_16250) 3421353..3421522 + 170 Protein_3193 hypothetical protein -
N7922_RS16255 (N7922_16255) 3421450..3421668 + 219 WP_001040187.1 translation initiation factor IF-1 -
N7922_RS16260 (N7922_16260) 3421828..3422271 + 444 WP_088237186.1 DUF2384 domain-containing protein Antitoxin
N7922_RS16265 (N7922_16265) 3422268..3422744 + 477 WP_263097309.1 RES domain-containing protein Toxin
N7922_RS16270 (N7922_16270) 3422907..3425126 + 2220 WP_263097310.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
N7922_RS16275 (N7922_16275) 3425303..3426691 + 1389 WP_263097312.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-144)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17662.18 Da        Isoelectric Point: 6.2104

>T259703 WP_263097309.1 NZ_CP106754:3422268-3422744 [Kosakonia sp. ML.JS2a]
MIFYRLVTHRYASEAWTGSGANLYGGRWNHKGHPAVYVASSISLAALEMLVHVHSDSILTQYGLFSIEIPDNDIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSGVALVLPSCVVPLENNAMLNPQHPVFSKQLKTVKALPFSFDTRLVNQITVR

Download         Length: 477 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16424.85 Da        Isoelectric Point: 9.9132

>AT259703 WP_088237186.1 NZ_CP106754:3421828-3422271 [Kosakonia sp. ML.JS2a]
MRTWSPDQKPAENALWRFAGFPANRGLKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSTGRTLTPE
ESERIARLVRVVDAAVQFFGNKKMAYDWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References