Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2194339..2194537 Replicon chromosome
Accession NZ_CP106754
Organism Kosakonia sp. ML.JS2a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2194435..2194537 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2194339..2194537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7922_RS10525 (N7922_10525) 2189576..2191651 + 2076 WP_263100479.1 oligopeptidase B -
N7922_RS10530 (N7922_10530) 2191633..2192295 - 663 WP_263100480.1 exodeoxyribonuclease X -
N7922_RS10535 (N7922_10535) 2192307..2192537 - 231 WP_263100481.1 DNA polymerase III subunit theta -
N7922_RS10540 (N7922_10540) 2192675..2193049 + 375 WP_263100482.1 CopC domain-containing protein YobA -
N7922_RS10545 (N7922_10545) 2193052..2193921 + 870 WP_263100483.1 copper homeostasis membrane protein CopD -
N7922_RS10550 (N7922_10550) 2193940..2194278 + 339 WP_263100484.1 YebY family protein -
- 2194339..2194537 - 199 - - Antitoxin
- 2194435..2194537 + 103 - - Toxin
N7922_RS10555 (N7922_10555) 2194691..2194852 - 162 WP_263100485.1 hypothetical protein -
N7922_RS10560 (N7922_10560) 2195053..2195997 - 945 WP_263100486.1 VirK/YbjX family protein -
N7922_RS10565 (N7922_10565) 2196171..2196815 + 645 WP_263100487.1 protein-serine/threonine phosphatase -
N7922_RS10570 (N7922_10570) 2196816..2197007 - 192 WP_263100488.1 YebW family protein -
N7922_RS10575 (N7922_10575) 2197113..2197352 - 240 WP_061496641.1 YebV family protein -
N7922_RS10580 (N7922_10580) 2197468..2198907 - 1440 WP_263100489.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T259699 NZ_CP106754:2194435-2194537 [Kosakonia sp. ML.JS2a]
GCCAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 199 bp

>AT259699 NZ_CP106754:c2194537-2194339 [Kosakonia sp. ML.JS2a]
AAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTGGCACTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCGCGACAAAAGTGGTCAAAA
AAATCAGGTTATCGTCACGCTTCAAAATGTTAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References