Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 900504..901167 Replicon chromosome
Accession NZ_CP106754
Organism Kosakonia sp. ML.JS2a

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N7922_RS04295 Protein ID WP_263099400.1
Coordinates 900751..901167 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag N7922_RS04290 Protein ID WP_263099399.1
Coordinates 900504..900770 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7922_RS04270 (N7922_04270) 896049..897482 - 1434 WP_263099397.1 6-phospho-beta-glucosidase -
N7922_RS04275 (N7922_04275) 897600..898328 - 729 WP_263100829.1 MurR/RpiR family transcriptional regulator -
N7922_RS04280 (N7922_04280) 898567..899226 + 660 WP_263099398.1 hemolysin III family protein -
N7922_RS04285 (N7922_04285) 899272..900255 - 984 WP_061493247.1 tRNA-modifying protein YgfZ -
N7922_RS04290 (N7922_04290) 900504..900770 + 267 WP_263099399.1 FAD assembly factor SdhE Antitoxin
N7922_RS04295 (N7922_04295) 900751..901167 + 417 WP_263099400.1 protein YgfX Toxin
N7922_RS04300 (N7922_04300) 901186..901707 - 522 WP_263099401.1 flavodoxin FldB -
N7922_RS04305 (N7922_04305) 901806..902702 + 897 WP_088237748.1 site-specific tyrosine recombinase XerD -
N7922_RS04310 (N7922_04310) 902726..903436 + 711 WP_263099402.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N7922_RS04315 (N7922_04315) 903442..905175 + 1734 WP_263099403.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16389.44 Da        Isoelectric Point: 11.4553

>T259696 WP_263099400.1 NZ_CP106754:900751-901167 [Kosakonia sp. ML.JS2a]
VVLWQSDLRVSWRAQWLSLLLHGLVAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGEIKLLMESRLRWQGV
EWHIVGAPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRMLSQKPAQGLR

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10455.89 Da        Isoelectric Point: 5.6062

>AT259696 WP_263099399.1 NZ_CP106754:900504-900770 [Kosakonia sp. ML.JS2a]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQLFVRLLESDDPDLFNWLMNHGKPQDAGLQRMVQVIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References