Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 365211..365910 Replicon chromosome
Accession NZ_CP106754
Organism Kosakonia sp. ML.JS2a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N7922_RS01625 Protein ID WP_263098977.1
Coordinates 365211..365600 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7922_RS01630 Protein ID WP_263098978.1
Coordinates 365593..365910 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7922_RS01605 (N7922_01605) 360702..361760 - 1059 WP_263098973.1 class I SAM-dependent methyltransferase -
N7922_RS01610 (N7922_01610) 361833..362222 - 390 WP_263098974.1 hypothetical protein -
N7922_RS01615 (N7922_01615) 362722..363771 - 1050 WP_263098975.1 AI-2E family transporter -
N7922_RS01620 (N7922_01620) 363884..365122 + 1239 WP_263098976.1 MFS transporter -
N7922_RS01625 (N7922_01625) 365211..365600 + 390 WP_263098977.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7922_RS01630 (N7922_01630) 365593..365910 + 318 WP_263098978.1 helix-turn-helix domain-containing protein Antitoxin
N7922_RS01635 (N7922_01635) 365982..366539 - 558 WP_263098979.1 DcrB family lipoprotein -
N7922_RS01640 (N7922_01640) 366612..367277 - 666 WP_263098980.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
N7922_RS01645 (N7922_01645) 367465..367710 + 246 WP_263098981.1 sulfurtransferase TusA -
N7922_RS01650 (N7922_01650) 367707..369926 - 2220 WP_263098982.1 Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA -
N7922_RS01655 (N7922_01655) 370002..370628 - 627 WP_263098983.1 lysoplasmalogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-89)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14786.13 Da        Isoelectric Point: 6.7105

>T259695 WP_263098977.1 NZ_CP106754:365211-365600 [Kosakonia sp. ML.JS2a]
MGIYLTMEFDQERRRVRISDKTLCKTAAAIIAGLHGDRLGKFTYKKRIALPAVSSRDGARAIVFFHEGDNLFFFDMYVKS
ELSKKKGKELEEDEIDAYCAVAKDFMVMPEETLARLLKSDDLIEVKCHE

Download         Length: 390 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11818.65 Da        Isoelectric Point: 10.6093

>AT259695 WP_263098978.1 NZ_CP106754:365593-365910 [Kosakonia sp. ML.JS2a]
MSDHLKRIQAMAKRYNKLGVVQDETVASINEAIEARNIPDVRPMTGMQIKQVRTHWKMSQAALARTVGMSVESVSKWERN
ESKPNNAALRILNTIEDKGPAIFLS

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References