Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 1973442..1974177 Replicon chromosome
Accession NC_016816
Organism Pantoea ananatis LMG 5342

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PANA5342_RS31785 Protein ID WP_041455870.1
Coordinates 1973442..1973834 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PANA5342_RS31790 Protein ID WP_014605595.1
Coordinates 1973824..1974177 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PANA5342_RS31770 1968742..1969914 - 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -
PANA5342_RS46445 1970016..1970168 - 153 WP_155644231.1 hypothetical protein -
PANA5342_RS31775 1970189..1972075 + 1887 WP_015700093.1 aliphatic sulfonate ABC transporter substrate-binding protein -
PANA5342_RS31780 1972170..1973117 + 948 WP_015700094.1 sulfonate ABC transporter substrate-binding protein -
PANA5342_RS31785 1973442..1973834 + 393 WP_041455870.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PANA5342_RS31790 1973824..1974177 + 354 WP_014605595.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PANA5342_RS31795 1974554..1975732 - 1179 WP_015700096.1 tyrosine-type recombinase/integrase -
PANA5342_RS31805 1975893..1977971 - 2079 WP_015700097.1 DNA cytosine methyltransferase -
PANA5342_RS31810 1977968..1978840 - 873 WP_015700098.1 phage N-6-adenine-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(8-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14826.24 Da        Isoelectric Point: 9.8572

>T25969 WP_041455870.1 NC_016816:1973442-1973834 [Pantoea ananatis LMG 5342]
MGFTLYVHNVLTKCLKKTRLTDSVLCYAAVDVITGVFEAELGGGVIKKRLALHQGKRGGVRTVILFRQGTNLVYYDGWVK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T25969 NC_016816:1973442-1973834 [Pantoea ananatis LMG 5342]
ATGGGTTTTACGCTTTATGTTCATAACGTTTTGACAAAGTGTTTAAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGTTGACGTTATTACTGGCGTGTTTGAGGCTGAATTAGGCGGTGGCGTTATTAAAAAGCGCCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGTGCGAACGGTCATCTTATTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGTTAAA
AACTTGTCGAGGAAATACGCCAGGGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGCAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13096.14 Da        Isoelectric Point: 7.2076

>AT25969 WP_014605595.1 NC_016816:1973824-1974177 [Pantoea ananatis LMG 5342]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT25969 NC_016816:1973824-1974177 [Pantoea ananatis LMG 5342]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATGA
AGAAGTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
CTGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGC
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTACAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATCAAGGTATCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References