Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4333703..4334961 | Replicon | chromosome |
Accession | NZ_CP106745 | ||
Organism | Pseudomonas aeruginosa strain PALA17 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PALA17_RS20310 | Protein ID | WP_012614407.1 |
Coordinates | 4333703..4334458 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PALA17_RS20315 | Protein ID | WP_003086329.1 |
Coordinates | 4334593..4334961 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA17_RS20300 (PALA17_04039) | 4328876..4331419 | + | 2544 | WP_003112526.1 | acyl-homoserine-lactone acylase QuiP | - |
PALA17_RS20305 (PALA17_04040) | 4331574..4332935 | - | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
PALA17_RS20310 (PALA17_04041) | 4333703..4334458 | - | 756 | WP_012614407.1 | RES family NAD+ phosphorylase | Toxin |
PALA17_RS20315 (PALA17_04042) | 4334593..4334961 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PALA17_RS20320 (PALA17_04043) | 4335034..4336320 | - | 1287 | WP_012614408.1 | FAD-binding oxidoreductase | - |
PALA17_RS20325 (PALA17_04044) | 4336376..4337965 | - | 1590 | WP_003125055.1 | aldehyde dehydrogenase family protein | - |
PALA17_RS20330 (PALA17_04045) | 4338044..4338520 | + | 477 | WP_003112531.1 | hypothetical protein | - |
PALA17_RS20335 | 4338523..4338798 | - | 276 | WP_169057979.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28250.37 Da Isoelectric Point: 7.7294
>T259686 WP_012614407.1 NZ_CP106745:c4334458-4333703 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT259686 WP_003086329.1 NZ_CP106745:c4334961-4334593 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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