Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 88452..89028 Replicon plasmid unnamed2
Accession NZ_CP106737
Organism Roseovarius sp. HL-MP18

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N7U68_RS00415 Protein ID WP_263046752.1
Coordinates 88738..89028 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A840CDQ2
Locus tag N7U68_RS00410 Protein ID WP_074838673.1
Coordinates 88452..88751 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7U68_RS00385 (N7U68_00385) 83504..84298 + 795 WP_263046748.1 pyrroline-5-carboxylate reductase dimerization domain-containing protein -
N7U68_RS00390 (N7U68_00390) 84494..84883 + 390 WP_263046749.1 DUF3768 domain-containing protein -
N7U68_RS00395 (N7U68_00395) 85039..87021 + 1983 WP_263046750.1 ParB/RepB/Spo0J family partition protein -
N7U68_RS00400 (N7U68_00400) 87098..87691 + 594 WP_121068269.1 regulator -
N7U68_RS00405 (N7U68_00405) 87691..88347 + 657 WP_263046751.1 hypothetical protein -
N7U68_RS00410 (N7U68_00410) 88452..88751 + 300 WP_074838673.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N7U68_RS00415 (N7U68_00415) 88738..89028 + 291 WP_263046752.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7U68_RS00420 (N7U68_00420) 89135..93397 + 4263 WP_263046753.1 strawberry notch family protein -
N7U68_RS00425 (N7U68_00425) 93520..93906 + 387 WP_263046754.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..242241 242241


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-54)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10886.43 Da        Isoelectric Point: 4.3516

>T259657 WP_263046752.1 NZ_CP106737:88738-89028 [Roseovarius sp. HL-MP18]
MPNLDGPDLEWKATAIADLLAIIDYISDDNPDAAQVLKDEIEHKTSLLPERPQMYRAGRVDGTREMVVRPNYIVVYAESP
EMVTILRVLHAAQQWP

Download         Length: 291 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10393.80 Da        Isoelectric Point: 5.0028

>AT259657 WP_074838673.1 NZ_CP106737:88452-88751 [Roseovarius sp. HL-MP18]
MPAQTSMLHVRVDDQLKAQASDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRAKVQEALDDPSPTTPH
AKAMQDAQALIDGKRLAKS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A840CDQ2

References