Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 356389..357116 Replicon chromosome
Accession NZ_CP106736
Organism Silvimonas sp. 17_6

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag N7220_RS01550 Protein ID WP_283149714.1
Coordinates 356389..356574 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag N7220_RS01555 Protein ID WP_283149715.1
Coordinates 356697..357116 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7220_RS01530 352127..352870 + 744 WP_283149710.1 SOS response-associated peptidase -
N7220_RS01535 352904..353194 + 291 WP_283149711.1 hypothetical protein -
N7220_RS01540 353244..353906 + 663 WP_283149712.1 SOS response-associated peptidase family protein -
N7220_RS01545 353947..356223 + 2277 WP_283149713.1 P-loop NTPase fold protein -
N7220_RS01550 356389..356574 + 186 WP_283149714.1 type II toxin-antitoxin system HicA family toxin Toxin
N7220_RS01555 356697..357116 + 420 WP_283149715.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
N7220_RS01560 357258..358058 - 801 WP_283149716.1 DNA adenine methylase -
N7220_RS01565 358461..358979 + 519 WP_283149717.1 hypothetical protein -
N7220_RS01570 359069..359557 - 489 WP_283149718.1 M23 family metallopeptidase -
N7220_RS01575 359618..359911 - 294 WP_283149719.1 hypothetical protein -
N7220_RS01580 359908..360246 - 339 WP_283149720.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 352127..399206 47079


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-67)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 6918.99 Da        Isoelectric Point: 10.9319

>T259654 WP_283149714.1 NZ_CP106736:356389-356574 [Silvimonas sp. 17_6]
MKYSEFRKWLKQQGATFEKHRAGSSHYRVTLNGKTTIFPDHGSKEIGTGLVQAIKKQLGVK

Download         Length: 186 bp

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15665.19 Da        Isoelectric Point: 5.2525

>AT259654 WP_283149715.1 NZ_CP106736:356697-357116 [Silvimonas sp. 17_6]
MLTYPVSLTRDDNDTFLVTFPDIPEAITVGDDEPQALASALEALEAALDIYFDEKRQIPMPSKIGRDHRTVTLPVLVTAK
VFLANEMLRQGVKKSELARRMDIHMPQVDRLLDLKHSSKIELVEVALQKLGKRLDITVN

Download         Length: 420 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References