Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 657190..657749 Replicon chromosome
Accession NZ_CP106735
Organism Reichenbachiella sp. Wsw4-B4

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N7E81_RS02395 Protein ID WP_263053117.1
Coordinates 657190..657459 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7E81_RS02400 Protein ID WP_263051685.1
Coordinates 657462..657749 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E81_RS02370 (N7E81_02370) 652745..653167 + 423 WP_263051681.1 immunity 63 family protein -
N7E81_RS02375 (N7E81_02375) 653448..654467 - 1020 WP_263049646.1 IS110 family transposase -
N7E81_RS02380 (N7E81_02380) 654737..654985 + 249 WP_263051682.1 type II toxin-antitoxin system ParD family antitoxin -
N7E81_RS02385 (N7E81_02385) 654978..655274 + 297 WP_263051683.1 type II toxin-antitoxin system RelE/ParE family toxin -
N7E81_RS02390 (N7E81_02390) 655525..656979 + 1455 WP_263051684.1 hypothetical protein -
N7E81_RS02395 (N7E81_02395) 657190..657459 + 270 WP_263053117.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E81_RS02400 (N7E81_02400) 657462..657749 + 288 WP_263051685.1 putative addiction module antidote protein Antitoxin
N7E81_RS02405 (N7E81_02405) 658243..658623 - 381 WP_263051686.1 hypothetical protein -
N7E81_RS02410 (N7E81_02410) 658620..659147 - 528 WP_263051687.1 hypothetical protein -
N7E81_RS02415 (N7E81_02415) 659498..660373 + 876 WP_263051688.1 META domain-containing protein -
N7E81_RS02420 (N7E81_02420) 660941..661591 + 651 WP_263051689.1 peroxiredoxin-like family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(6-79)

Antitoxin

Uncharacterized protein HI1420

(6-92)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10530.17 Da        Isoelectric Point: 10.2492

>T259652 WP_263053117.1 NZ_CP106735:657190-657459 [Reichenbachiella sp. Wsw4-B4]
MRKLKDKRAKAKILFRIQRIEEHGNFGDCEPVGQGISELRIHYAKGYRVYLKDVNGRIVFLLNRGDKSSQHKDIDKAKQL
WLDYKNEIE

Download         Length: 270 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10272.75 Da        Isoelectric Point: 5.6863

>AT259652 WP_263051685.1 NZ_CP106735:657462-657749 [Reichenbachiella sp. Wsw4-B4]
MATKRTTKFDIAEYLENDEMMAEYLNSVLEDGDSADILTAIGHIAKAQGMTKIAAETGLSRPSLYKALSKGAKPQFDTVL
KVLRAVGSNLHVETA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References