259630

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 3352894..3353405 Replicon chromosome
Accession NZ_CP106679
Organism Reichenbachiella sp. BKB1-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N6H18_RS14170 Protein ID WP_262308933.1
Coordinates 3353145..3353405 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N6H18_RS14165 Protein ID WP_262308932.1
Coordinates 3352894..3353148 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6H18_RS14135 (N6H18_14135) 3348438..3348644 - 207 WP_262308926.1 sulfur carrier protein ThiS -
N6H18_RS14140 (N6H18_14140) 3348813..3350135 - 1323 WP_262308927.1 hypothetical protein -
N6H18_RS14145 (N6H18_14145) 3350205..3350822 - 618 WP_262308928.1 response regulator transcription factor -
N6H18_RS14150 (N6H18_14150) 3350919..3351761 - 843 WP_262308929.1 S1-like domain-containing RNA-binding protein -
N6H18_RS14155 (N6H18_14155) 3351792..3352229 - 438 WP_262308930.1 heme-binding protein -
N6H18_RS14160 (N6H18_14160) 3352374..3352754 + 381 WP_262308931.1 response regulator -
N6H18_RS14165 (N6H18_14165) 3352894..3353148 + 255 WP_262308932.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N6H18_RS14170 (N6H18_14170) 3353145..3353405 + 261 WP_262308933.1 Txe/YoeB family addiction module toxin Toxin
N6H18_RS14175 (N6H18_14175) 3353756..3354157 - 402 WP_262308934.1 OsmC family protein -
N6H18_RS14180 (N6H18_14180) 3355977..3356282 - 306 WP_262308935.1 CRISPR-associated endonuclease Cas2 -
N6H18_RS14185 (N6H18_14185) 3356297..3357214 - 918 WP_262308936.1 type II CRISPR-associated endonuclease Cas1 -
N6H18_RS14190 (N6H18_14190) 3357296..3357913 - 618 WP_262308937.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10567.37 Da        Isoelectric Point: 8.6835

>T259630 WP_262308933.1 NZ_CP106679:3353145-3353405 [Reichenbachiella sp. BKB1-1]
MTKLIKFSSHAWLDYIHWQKSDKEMKQLIDKLCLSILETPYQGLGYPQPLSYELNQIWCRRINMEHRLVYRINKDQIEIL
QCRLHY

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9786.10 Da        Isoelectric Point: 8.6094

>AT259630 WP_262308932.1 NZ_CP106679:3352894-3353148 [Reichenbachiella sp. BKB1-1]
MDHTTYTNFRQNLKSFMDRVMNDRIPLLVTRAHGQDVVVLSKADFDSIHETFYLLKNPRNAQRIFESLSELRDGGGFEKS
IQKP

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References