Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 395459..395985 Replicon plasmid pML.8a3
Accession NZ_CP106661
Organism Pantoea dispersa strain ML.8a3

Toxin (Protein)


Gene name relE Uniprot ID A0A8E1S2F7
Locus tag N7977_RS20755 Protein ID WP_021509424.1
Coordinates 395459..395746 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8E1S2J3
Locus tag N7977_RS20760 Protein ID WP_058759167.1
Coordinates 395746..395985 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7977_RS20740 (N7977_20740) 391292..392074 - 783 WP_262258154.1 acetolactate decarboxylase -
N7977_RS20745 (N7977_20745) 392179..393060 + 882 WP_262258155.1 LysR family transcriptional regulator -
N7977_RS20750 (N7977_20750) 393559..395340 + 1782 WP_262258156.1 sensor domain-containing phosphodiesterase -
N7977_RS20755 (N7977_20755) 395459..395746 - 288 WP_021509424.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7977_RS20760 (N7977_20760) 395746..395985 - 240 WP_058759167.1 type II toxin-antitoxin system antitoxin RelB Antitoxin
N7977_RS20765 (N7977_20765) 396113..398815 - 2703 WP_262258158.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..742161 742161


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-78)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11192.19 Da        Isoelectric Point: 10.1967

>T259611 WP_021509424.1 NZ_CP106661:c395746-395459 [Pantoea dispersa]
MAYFLDFDERALKEWRKLGSTVREQLKKKLAEVLEAPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERAEVYNEAVKRIL

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9071.48 Da        Isoelectric Point: 4.5230

>AT259611 WP_058759167.1 NZ_CP106661:c395985-395746 [Pantoea dispersa]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIAENERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References