Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2222706..2222874 Replicon chromosome
Accession NZ_CP106658
Organism Klebsiella michiganensis strain 8BG

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2222764..2222867 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2222706..2222874 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7918_RS10615 (N7918_10615) 2217833..2219893 + 2061 WP_014229840.1 oligopeptidase B -
N7918_RS10620 (N7918_10620) 2219900..2220559 - 660 WP_014229839.1 exodeoxyribonuclease X -
N7918_RS10625 (N7918_10625) 2220638..2220868 - 231 WP_004103351.1 DNA polymerase III subunit theta -
N7918_RS10630 (N7918_10630) 2221004..2221378 + 375 WP_014229838.1 CopC domain-containing protein YobA -
N7918_RS10635 (N7918_10635) 2221383..2222252 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
N7918_RS10640 (N7918_10640) 2222269..2222607 + 339 WP_004103344.1 YebY family protein -
- 2222706..2222874 - 169 - - Antitoxin
- 2222764..2222867 + 104 - - Toxin
N7918_RS10645 (N7918_10645) 2222992..2223951 - 960 WP_088168007.1 spore coat protein U domain-containing protein -
N7918_RS10650 (N7918_10650) 2223966..2226296 - 2331 WP_262191332.1 fimbria/pilus outer membrane usher protein -
N7918_RS10655 (N7918_10655) 2226299..2227063 - 765 WP_262191333.1 fimbria/pilus periplasmic chaperone -
N7918_RS10660 (N7918_10660) 2227082..2227600 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T259594 NZ_CP106658:2222764-2222867 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT259594 NZ_CP106658:c2222874-2222706 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References