259565

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 2689928..2690565 Replicon chromosome
Accession NZ_CP104992
Organism Rhizobium sp. CC-CFT758

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag N7E02_RS21030 Protein ID WP_286579550.1
Coordinates 2690197..2690565 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag N7E02_RS21025 Protein ID WP_286579549.1
Coordinates 2689928..2690200 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E02_RS21000 (N7E02_21000) 2685983..2686825 + 843 WP_286583964.1 metallophosphoesterase -
N7E02_RS21005 (N7E02_21005) 2686826..2687515 - 690 WP_286579545.1 YafY family protein -
N7E02_RS21010 (N7E02_21010) 2687645..2688277 + 633 WP_286579546.1 LysE family translocator -
N7E02_RS21015 (N7E02_21015) 2688438..2688881 + 444 WP_286579547.1 cytochrome c -
N7E02_RS21020 (N7E02_21020) 2688964..2689875 + 912 WP_286579548.1 cytochrome c -
N7E02_RS21025 (N7E02_21025) 2689928..2690200 + 273 WP_286579549.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N7E02_RS21030 (N7E02_21030) 2690197..2690565 + 369 WP_286579550.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
N7E02_RS21035 (N7E02_21035) 2690593..2691162 - 570 WP_286579551.1 DJ-1/PfpI family protein -
N7E02_RS21040 (N7E02_21040) 2691220..2691708 - 489 WP_286579552.1 GNAT family N-acetyltransferase -
N7E02_RS21045 (N7E02_21045) 2691952..2692143 - 192 WP_286579553.1 hypothetical protein -
N7E02_RS21050 (N7E02_21050) 2692266..2692703 - 438 WP_286579554.1 hypothetical protein -
N7E02_RS21055 (N7E02_21055) 2692840..2693256 - 417 WP_286579555.1 helix-turn-helix domain-containing protein -
N7E02_RS21060 (N7E02_21060) 2693393..2693665 + 273 WP_286579557.1 Ni(II)/Co(II)-sensing transcriptional repressor DmeR -
N7E02_RS21065 (N7E02_21065) 2693717..2694688 + 972 WP_286579558.1 CDF family Co(II)/Ni(II) efflux transporter DmeF -
N7E02_RS21070 (N7E02_21070) 2694747..2695010 - 264 WP_286579559.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-113)

Antitoxin

SpoVT-AbrB domain

(10-54)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13226.14 Da        Isoelectric Point: 7.1668

>T259565 WP_286579550.1 NZ_CP104992:2690197-2690565 [Rhizobium sp. CC-CFT758]
MMVRSNVPNRGDVFWIDPNPVAGREIKDRHRFVVITPREINALGVAMTVPITSGGGFTRNVGLAVPISGHDTTGVAVCNQ
VRSFDIPARVQSKTARYIETLDQPTMDEIVARVVSAIDPAAE

Download         Length: 369 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9778.40 Da        Isoelectric Point: 7.0133

>AT259565 WP_286579549.1 NZ_CP104992:2689928-2690200 [Rhizobium sp. CC-CFT758]
MAMSITTKIRKQGGAAIVTIPPAVLKTMQLEIGDQLSLEMSEGELVVKPLRSAKRRYKLSELLEGKDAMSRLNADVAWAT
EGDPVGHEIS

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References