259562

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2420268..2420751 Replicon chromosome
Accession NZ_CP104992
Organism Rhizobium sp. CC-CFT758

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag N7E02_RS19630 Protein ID WP_286579306.1
Coordinates 2420268..2420537 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag N7E02_RS19635 Protein ID WP_286579307.1
Coordinates 2420521..2420751 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E02_RS19600 (N7E02_19600) 2415671..2416516 - 846 WP_286579300.1 L,D-transpeptidase -
N7E02_RS19605 (N7E02_19605) 2416747..2417370 + 624 WP_286579301.1 DNA-3-methyladenine glycosylase I -
N7E02_RS19610 (N7E02_19610) 2417425..2418135 - 711 WP_286579302.1 HAD family hydrolase -
N7E02_RS19615 (N7E02_19615) 2418396..2418770 - 375 WP_286579303.1 DUF305 domain-containing protein -
N7E02_RS19620 (N7E02_19620) 2418822..2419283 - 462 WP_286579304.1 hypothetical protein -
N7E02_RS19625 (N7E02_19625) 2419512..2420264 - 753 WP_286579305.1 hypothetical protein -
N7E02_RS19630 (N7E02_19630) 2420268..2420537 - 270 WP_286579306.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E02_RS19635 (N7E02_19635) 2420521..2420751 - 231 WP_286579307.1 DUF6290 family protein Antitoxin
N7E02_RS19640 (N7E02_19640) 2420886..2422441 + 1556 Protein_2301 histidine--tRNA ligase -
N7E02_RS19645 (N7E02_19645) 2422660..2423769 + 1110 WP_286579308.1 ATP phosphoribosyltransferase regulatory subunit -
N7E02_RS19650 (N7E02_19650) 2423769..2424465 + 697 Protein_2303 ATP phosphoribosyltransferase -
N7E02_RS19655 (N7E02_19655) 2424483..2425091 + 609 WP_286579309.1 methyltransferase domain-containing protein -
N7E02_RS19660 (N7E02_19660) 2425171..2425620 - 450 WP_286579310.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(5-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10725.50 Da        Isoelectric Point: 10.5786

>T259562 WP_286579306.1 NZ_CP104992:c2420537-2420268 [Rhizobium sp. CC-CFT758]
MAWKIDFQATAIKQLKKMGHNESARIRDFLHTRVKPLDNPRQLGEALQGPRFKHLWRYKVGDYRIICDIQDERLVVLVVE
VDHRRQIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8835.88 Da        Isoelectric Point: 4.0236

>AT259562 WP_286579307.1 NZ_CP104992:c2420751-2420521 [Rhizobium sp. CC-CFT758]
MNKRVTIEMPDEMLKLVEEYAAEAGAAPDAYLRDVIEQHLEDLHDIALAEAAMERIRNGERTYTWEEMERELGLED

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References