Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1056100..1056641 Replicon chromosome
Accession NZ_CP104992
Organism Rhizobium sp. CC-CFT758

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N7E02_RS13185 Protein ID WP_286582403.1
Coordinates 1056100..1056393 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N7E02_RS13190 Protein ID WP_286582405.1
Coordinates 1056390..1056641 (-) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E02_RS13170 (N7E02_13165) 1053011..1053505 + 495 WP_286582401.1 MarR family transcriptional regulator -
N7E02_RS13175 (N7E02_13170) 1053528..1054703 + 1176 WP_286583806.1 multidrug effflux MFS transporter -
N7E02_RS13180 (N7E02_13175) 1054762..1055985 - 1224 WP_286582402.1 argininosuccinate synthase -
N7E02_RS13185 (N7E02_13180) 1056100..1056393 - 294 WP_286582403.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E02_RS13190 (N7E02_13185) 1056390..1056641 - 252 WP_286582405.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
N7E02_RS13195 (N7E02_13190) 1056755..1057612 + 858 WP_286582407.1 SDR family NAD(P)-dependent oxidoreductase -
N7E02_RS13200 (N7E02_13195) 1057684..1058325 + 642 WP_286582408.1 LysE family translocator -
N7E02_RS13205 (N7E02_13200) 1058355..1059590 - 1236 WP_286582409.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
N7E02_RS13210 (N7E02_13205) 1059831..1060334 - 504 WP_286582410.1 invasion associated locus B family protein -
N7E02_RS13215 (N7E02_13210) 1060655..1061213 + 559 Protein_1041 sigma-70 family RNA polymerase sigma factor -
N7E02_RS13220 (N7E02_13215) 1061221..1061625 - 405 WP_286582412.1 YkvA family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-92)

Antitoxin

(5-81)


Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 11610.33 Da        Isoelectric Point: 8.4984

>T259561 WP_286582403.1 NZ_CP104992:c1056393-1056100 [Rhizobium sp. CC-CFT758]
MKALVFSPKAEADIDDIYDYTEQHWGFENAEVYTFELRDACRSLVEGPRHGRKIGDEIRRNYFVLSCKAHFIIYRETVSR
IVIVRILHQRMNVRRHL

Download         Length: 294 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9468.47 Da        Isoelectric Point: 4.2316

>AT259561 WP_286582405.1 NZ_CP104992:c1056641-1056390 [Rhizobium sp. CC-CFT758]
VGEIKSIKVDEELTAFVRKQVDEGRYASESEVVEEALRLLKESEEEAIEAIRTAIDEGEASGEPQPFDFDAFIERKRVQR
AQR

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References