Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 299690..300267 Replicon chromosome
Accession NZ_CP104992
Organism Rhizobium sp. CC-CFT758

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag N7E02_RS09555 Protein ID WP_286581654.1
Coordinates 299690..300028 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag N7E02_RS09560 Protein ID WP_286581656.1
Coordinates 300025..300267 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E02_RS09540 (N7E02_09540) 296583..297636 + 1054 Protein_315 low specificity L-threonine aldolase -
N7E02_RS09545 (N7E02_09545) 297641..298495 - 855 WP_286581651.1 LysR family transcriptional regulator -
N7E02_RS09550 (N7E02_09550) 298686..299684 + 999 WP_286581653.1 bile acid:sodium symporter family protein -
N7E02_RS09555 (N7E02_09555) 299690..300028 - 339 WP_286581654.1 endoribonuclease MazF Toxin
N7E02_RS09560 (N7E02_09560) 300025..300267 - 243 WP_286581656.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N7E02_RS09565 (N7E02_09565) 300408..300889 - 482 Protein_320 Hsp20 family protein -
N7E02_RS09570 (N7E02_09570) 301194..302357 + 1164 WP_286581657.1 hypothetical protein -
N7E02_RS09575 (N7E02_09575) 302597..303580 - 984 WP_286581658.1 AraC family transcriptional regulator -
N7E02_RS09580 (N7E02_09580) 303764..304654 + 891 WP_286581659.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-103)

Antitoxin

SpoVT-AbrB domain

(6-48)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12069.84 Da        Isoelectric Point: 9.6283

>T259560 WP_286581654.1 NZ_CP104992:c300028-299690 [Rhizobium sp. CC-CFT758]
VSAEEYVPQAGDIVWLDFSPQVGHEQAGRRPAVVLSPVAYNRFGLMLCCPLTTKVKGYPFEVTIEGGRGGVVLADQVKSL
DWKARNAQRKGAVSSSELSQIRAKSSALIGRP

Download         Length: 339 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8695.86 Da        Isoelectric Point: 4.1958

>AT259560 WP_286581656.1 NZ_CP104992:c300267-300025 [Rhizobium sp. CC-CFT758]
MRVTVKKWGNSASVRIPAAIMDAANLTLDTVVDITEENGRVIIEPVREDVVELDRLLGGITPDNQHDEIDFGAPVGKEAL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References