Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4123760..4124554 Replicon chromosome
Accession NZ_CP104976
Organism Enterobacter sp. 155105

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag N8O08_RS19990 Protein ID WP_194400898.1
Coordinates 4124033..4124554 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A156QBZ1
Locus tag N8O08_RS19985 Protein ID WP_063143245.1
Coordinates 4123760..4124029 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8O08_RS19960 (N8O08_19960) 4119279..4120550 + 1272 WP_223562320.1 DUF445 domain-containing protein -
N8O08_RS19965 (N8O08_19965) 4120547..4121623 - 1077 WP_223562319.1 DUF2955 domain-containing protein -
N8O08_RS19970 (N8O08_19970) 4121613..4122680 - 1068 WP_223563444.1 HlyD family secretion protein -
N8O08_RS19975 (N8O08_19975) 4122677..4123147 - 471 WP_194400897.1 MarR family transcriptional regulator -
N8O08_RS19980 (N8O08_19980) 4123398..4123517 - 120 Protein_3909 transcriptional regulator -
N8O08_RS19985 (N8O08_19985) 4123760..4124029 + 270 WP_063143245.1 DUF1778 domain-containing protein Antitoxin
N8O08_RS19990 (N8O08_19990) 4124033..4124554 + 522 WP_194400898.1 GNAT family N-acetyltransferase Toxin
N8O08_RS19995 (N8O08_19995) 4124605..4126020 - 1416 WP_223562318.1 aldehyde dehydrogenase family protein -
N8O08_RS20000 (N8O08_20000) 4126121..4127023 + 903 WP_223562317.1 LysR family transcriptional regulator -
N8O08_RS20005 (N8O08_20005) 4127010..4127489 - 480 WP_014882392.1 carboxymuconolactone decarboxylase family protein -
N8O08_RS20010 (N8O08_20010) 4127593..4128981 + 1389 WP_223562316.1 PLP-dependent aminotransferase family protein -
N8O08_RS20015 (N8O08_20015) 4129021..4129182 - 162 WP_032645487.1 DUF1127 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(88-150)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19790.88 Da        Isoelectric Point: 8.4279

>T259554 WP_194400898.1 NZ_CP104976:4124033-4124554 [Enterobacter sp. 155105]
VNDVKIGIFSEDVEYDLSQFDCGEESLNTFLAEHLKRQHRGKFLRGYVLTTREPKPRILGYYTLSGSCFEKAYLPSKTQQ
KRIPYKNVPSVTLGRLAIDKRIQGQGYGELLVIHAMKTVYLASFAVGIHGLFVEALNHKAKEFYLKMGFIPLLAENEFTL
FLPTKTFESVFEE

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10071.49 Da        Isoelectric Point: 5.8508

>AT259554 WP_063143245.1 NZ_CP104976:4123760-4124029 [Enterobacter sp. 155105]
MSALKKQRIDLRLTEDDKNMIEEAAAMTNQSISQFMVSTASERAAEVIDQHRRLVLSEASWNTVMDAISNPPAPNDRLKR
AAKRLLDME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A156QBZ1

References