Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 756859..757516 Replicon chromosome
Accession NZ_CP104976
Organism Enterobacter sp. 155105

Toxin (Protein)


Gene name cptA Uniprot ID W7P4L3
Locus tag N8O08_RS03650 Protein ID WP_023326024.1
Coordinates 757106..757516 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag N8O08_RS03645 Protein ID WP_006178375.1
Coordinates 756859..757125 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8O08_RS03620 (N8O08_03620) 752041..753474 - 1434 WP_223561484.1 6-phospho-beta-glucosidase BglA -
N8O08_RS03625 (N8O08_03625) 753591..754322 - 732 WP_223563527.1 MurR/RpiR family transcriptional regulator -
N8O08_RS03630 (N8O08_03630) 754374..754685 + 312 WP_223561483.1 N(4)-acetylcytidine aminohydrolase -
N8O08_RS03635 (N8O08_03635) 754851..755510 + 660 WP_023333307.1 hemolysin III family protein -
N8O08_RS03640 (N8O08_03640) 755584..756564 - 981 WP_223561482.1 tRNA-modifying protein YgfZ -
N8O08_RS03645 (N8O08_03645) 756859..757125 + 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
N8O08_RS03650 (N8O08_03650) 757106..757516 + 411 WP_023326024.1 protein YgfX Toxin
N8O08_RS03655 (N8O08_03655) 757523..758044 - 522 WP_223561481.1 flavodoxin FldB -
N8O08_RS03660 (N8O08_03660) 758146..759042 + 897 WP_023309098.1 site-specific tyrosine recombinase XerD -
N8O08_RS03665 (N8O08_03665) 759071..759784 + 714 WP_029740340.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N8O08_RS03670 (N8O08_03670) 759790..761523 + 1734 WP_223561480.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16063.06 Da        Isoelectric Point: 10.9468

>T259546 WP_023326024.1 NZ_CP104976:757106-757516 [Enterobacter sp. 155105]
VVLWQSDLRVSWRSQWMSLLLHGLVAAIVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT259546 WP_006178375.1 NZ_CP104976:756859-757125 [Enterobacter sp. 155105]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W7P4L3

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References