Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2231757..2232388 Replicon chromosome
Accession NZ_CP104973
Organism Phyllobacterium zundukense strain A18/3m

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8E88_RS23360 Protein ID WP_262292672.1
Coordinates 2231757..2232155 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8E88_RS23365 Protein ID WP_262292673.1
Coordinates 2232155..2232388 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E88_RS23340 (N8E88_23345) 2227226..2228146 - 921 WP_262292669.1 LysR family transcriptional regulator -
N8E88_RS23345 (N8E88_23350) 2228264..2229295 + 1032 WP_262292670.1 NAD(P)-dependent alcohol dehydrogenase -
N8E88_RS23350 (N8E88_23355) 2229406..2229618 - 213 WP_106718517.1 cold-shock protein -
N8E88_RS23355 (N8E88_23360) 2229952..2231736 + 1785 WP_262292671.1 ABC transporter ATP-binding protein/permease -
N8E88_RS23360 (N8E88_23365) 2231757..2232155 - 399 WP_262292672.1 tRNA(fMet)-specific endonuclease VapC Toxin
N8E88_RS23365 (N8E88_23370) 2232155..2232388 - 234 WP_262292673.1 antitoxin Antitoxin
N8E88_RS23370 (N8E88_23375) 2232477..2235962 - 3486 WP_262292674.1 carbamoyl-phosphate synthase large subunit -
N8E88_RS23375 (N8E88_23380) 2236290..2237219 + 930 WP_262292675.1 neutral zinc metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14843.19 Da        Isoelectric Point: 6.9576

>T259541 WP_262292672.1 NZ_CP104973:c2232155-2231757 [Phyllobacterium zundukense]
MLRYMLDTNICIYVMKSYPLQLREKFNALAEQLCISSITLGEMHYGTEKSARTVENLKAIEHFVSRLEVLPFAAGAAVHY
GQIRADLERAGTPCGSHDMQIGGHARSEGLVVVTNNMREFIRMPGVLTENWI

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8780.94 Da        Isoelectric Point: 5.0336

>AT259541 WP_262292673.1 NZ_CP104973:c2232388-2232155 [Phyllobacterium zundukense]
MTSSTVFTTNRSQAVRLPKAVAFPEDVHQVDILKIGQGRLVVPQGKRWDDLFTQGPRLSDDFMSEREQPVIEDREPL

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References