Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 1381926..1382439 Replicon chromosome
Accession NZ_CP104973
Organism Phyllobacterium zundukense strain A18/3m

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N8E88_RS19155 Protein ID WP_262295062.1
Coordinates 1381926..1382159 (+) Length 78 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N8E88_RS19160 Protein ID WP_262295063.1
Coordinates 1382152..1382439 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E88_RS19135 (N8E88_19140) 1377547..1378944 - 1398 WP_262295058.1 RsmB/NOP family class I SAM-dependent RNA methyltransferase -
N8E88_RS19140 (N8E88_19145) 1378941..1379912 - 972 WP_262295059.1 zinc metalloprotease HtpX -
N8E88_RS19145 (N8E88_19150) 1380008..1380259 + 252 WP_262295060.1 DUF1674 domain-containing protein -
N8E88_RS19150 (N8E88_19155) 1380269..1381663 - 1395 WP_262295061.1 MATE family efflux transporter -
N8E88_RS19155 (N8E88_19160) 1381926..1382159 + 234 WP_262295062.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E88_RS19160 (N8E88_19165) 1382152..1382439 + 288 WP_262295063.1 putative addiction module antidote protein Antitoxin
N8E88_RS19165 (N8E88_19170) 1382787..1384052 + 1266 WP_262295064.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
N8E88_RS19170 (N8E88_19175) 1384222..1386174 - 1953 WP_262295065.1 acetate--CoA ligase -
N8E88_RS19175 (N8E88_19180) 1386470..1387006 + 537 WP_262295066.1 D-Ala-D-Ala carboxypeptidase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-72)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 78 a.a.        Molecular weight: 8649.91 Da        Isoelectric Point: 9.7269

>T259540 WP_262295062.1 NZ_CP104973:1381926-1382159 [Phyllobacterium zundukense]
MIASRLERLAFGHAGDVQPVGHGISELRIHYGPGYRIYFQRRGDVIVVLLCGGDKSTQARDIRTAKLLAAEWREWNG

Download         Length: 234 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10280.82 Da        Isoelectric Point: 5.1088

>AT259540 WP_262295063.1 NZ_CP104973:1382152-1382439 [Phyllobacterium zundukense]
MVEKLIPYDPAEDLTTDDAIEVFLTDAFETGDAAYIARALGVVARAKGMTKIARKTGLAREQLYRSLSENGNPTLETTMA
VMKAIGFQITGKRAA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References