Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 754042..754589 Replicon plasmid p_unnamed1
Accession NZ_CP104972
Organism Phyllobacterium zundukense strain A18/3m

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N8E88_RS11190 Protein ID WP_262291806.1
Coordinates 754042..754335 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N8E88_RS11195 Protein ID WP_262291807.1
Coordinates 754335..754589 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E88_RS11170 (N8E88_11180) 751095..751568 + 474 WP_262291802.1 hypothetical protein -
N8E88_RS11175 (N8E88_11185) 751619..751891 + 273 WP_262291803.1 hypothetical protein -
N8E88_RS11180 (N8E88_11190) 752111..752695 - 585 WP_262291804.1 GNAT family N-acetyltransferase -
N8E88_RS11185 (N8E88_11195) 753161..753691 + 531 WP_262291805.1 dihydrofolate reductase family protein -
N8E88_RS11190 (N8E88_11200) 754042..754335 - 294 WP_262291806.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E88_RS11195 (N8E88_11205) 754335..754589 - 255 WP_262291807.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
N8E88_RS11200 (N8E88_11210) 754771..756048 - 1278 WP_262291808.1 adenylate/guanylate cyclase domain-containing protein -
N8E88_RS11205 (N8E88_11215) 756593..756958 + 366 WP_262291809.1 MmcQ/YjbR family DNA-binding protein -
N8E88_RS11210 (N8E88_11220) 757003..757222 - 220 Protein_755 antifreeze protein -
N8E88_RS11215 (N8E88_11225) 757495..757620 - 126 Protein_756 SulP family inorganic anion transporter -
N8E88_RS11220 (N8E88_11230) 757677..757931 + 255 Protein_757 SulP family inorganic anion transporter -
N8E88_RS11225 (N8E88_11235) 758040..758645 - 606 Protein_758 protein-L-isoaspartate(D-aspartate) O-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - flhA / fliQ / fliP / htpB 1..990469 990469


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11261.96 Da        Isoelectric Point: 6.3280

>T259538 WP_262291806.1 NZ_CP104972:c754335-754042 [Phyllobacterium zundukense]
MRFSLSVEAEEDIIVITEQGIRMFGTLQARRYHDDLFAVLELIAANPRMAREREEISPPVRIHPFKAHLIVCRIQENGTI
FVIRIRHGHEDWASEPA

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9325.46 Da        Isoelectric Point: 10.1451

>AT259538 WP_262291807.1 NZ_CP104972:c754589-754335 [Phyllobacterium zundukense]
MATMNVSLPDPMKDWVEAQARTGRYSNASDYVRDLIRRDQTRSDKIVAMQRFVDDGLKSGVGSRSKDELFAAAAARTETA
RGSK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References