Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 121623..123132 Replicon plasmid p_unnamed3
Accession NZ_CP104970
Organism Phyllobacterium zundukense strain A18/3m

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag N8E88_RS02355 Protein ID WP_262290929.1
Coordinates 122227..123132 (+) Length 302 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag N8E88_RS02350 Protein ID WP_262290928.1
Coordinates 121623..122237 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E88_RS02330 (N8E88_02335) 117542..118375 + 834 WP_262290924.1 carbohydrate ABC transporter permease -
N8E88_RS02335 (N8E88_02340) 118415..119671 + 1257 WP_262290925.1 ABC transporter substrate-binding protein -
N8E88_RS02340 (N8E88_02345) 119734..120540 + 807 WP_262290926.1 phosphodiesterase -
N8E88_RS02345 (N8E88_02350) 120537..121235 + 699 WP_262290927.1 HAD family hydrolase -
N8E88_RS02350 (N8E88_02355) 121623..122237 + 615 WP_262290928.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
N8E88_RS02355 (N8E88_02360) 122227..123132 + 906 WP_262290929.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
N8E88_RS02360 (N8E88_02365) 123828..125006 - 1179 WP_262290930.1 N-acetylglucosamine-6-phosphate deacetylase -
N8E88_RS02365 (N8E88_02370) 125003..126037 - 1035 WP_262290931.1 SIS domain-containing protein -
N8E88_RS02370 (N8E88_02375) 126065..126829 - 765 WP_262290932.1 GntR family transcriptional regulator -
N8E88_RS02375 (N8E88_02380) 126826..127710 - 885 WP_262290933.1 N-acetylglucosamine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..568546 568546


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(10-54)


Sequences

Toxin        


Download         Length: 302 a.a.        Molecular weight: 33862.88 Da        Isoelectric Point: 5.8656

>T259533 WP_262290929.1 NZ_CP104970:122227-123132 [Phyllobacterium zundukense]
MAREPKKNVGASVRARLLARSRTERVDFQILLTRYALERLLYRLSLSAHRDRFILKGAMLFVTWVADPFRPTRDLDLLGY
GENSPKAIAETFHVICTQPVDDDGVVFDVDGLEAVPIREEVEYGGVRVRTTAAIAGARIPIQVDIGFGDAVTPGPVDIEY
PSLLDAPAPRLRAYPVATVVAEKFEALVTLGMANSRLKDFYDLWWIAETFELERPTLVEAVRQTFARRGTELPKERPTGL
SDAYAEVWDRQWRAFLGRERMAAAPPSLATVVGDLGHLLLPLTEPLDGNWRWKPREGWIQP

Download         Length: 906 bp

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 22986.60 Da        Isoelectric Point: 9.9394

>AT259533 WP_262290928.1 NZ_CP104970:121623-122237 [Phyllobacterium zundukense]
MADTQRARALELLKARHMLRLKDFAAHGIGSETLARLIRDEEVVRPARGLYQLPDAATDVSHALAEASALVPKGIVCLTS
ALQFHELTLQMPSAVWMAIDRTAWRPKIDYPPIRFVRFTGFALTEGVERHRIEGVEVPITNPARSIVDCFRYRSKVGLDV
AMEGLREGLRRRKTTSDELWTYAKKARIWSTMRPYVEATVADGA

Download         Length: 615 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References