Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 650967..651643 Replicon plasmid p_unnamed1
Accession NZ_CP104967
Organism Phyllobacterium sp. A18/5-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8E89_RS21675 Protein ID WP_262263166.1
Coordinates 651218..651643 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8E89_RS21670 Protein ID WP_262263165.1
Coordinates 650967..651221 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E89_RS21640 (N8E89_21635) 646182..647105 - 924 WP_262263163.1 glyoxylate/hydroxypyruvate reductase A -
N8E89_RS21645 (N8E89_21640) 647164..648290 - 1127 Protein_641 acetylornithine deacetylase -
N8E89_RS21650 (N8E89_21645) 648558..649448 + 891 WP_262263164.1 GNAT family N-acetyltransferase -
N8E89_RS21655 (N8E89_21650) 649572..650436 - 865 Protein_643 alpha/beta fold hydrolase -
N8E89_RS21660 (N8E89_21655) 650616..650764 - 149 Protein_644 RES domain-containing protein -
N8E89_RS21665 (N8E89_21660) 650766..650864 - 99 Protein_645 recombinase family protein -
N8E89_RS21670 (N8E89_21665) 650967..651221 + 255 WP_262263165.1 plasmid stability protein stbC Antitoxin
N8E89_RS21675 (N8E89_21670) 651218..651643 + 426 WP_262263166.1 type II toxin-antitoxin system VapC family toxin Toxin
N8E89_RS21680 (N8E89_21675) 651832..652908 - 1077 WP_262263167.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
N8E89_RS21685 (N8E89_21680) 652905..653837 - 933 WP_262263168.1 PfkB family carbohydrate kinase -
N8E89_RS21690 (N8E89_21685) 653837..654853 - 1017 WP_262263169.1 SIS domain-containing protein -
N8E89_RS21695 (N8E89_21690) 654861..655705 - 845 Protein_651 carbohydrate ABC transporter permease -
N8E89_RS21700 (N8E89_21695) 655705..656586 - 882 WP_262263170.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliP / flgI / fliI / motA / gmd / htpB / flhA / fliQ 1..1594332 1594332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15122.28 Da        Isoelectric Point: 4.4227

>T259530 WP_262263166.1 NZ_CP104967:651218-651643 [Phyllobacterium sp. A18/5-2]
MILIDTNVISEPWRLTPDARVLAWIDAQAIETLYLSAVTIAEVGFGIASMPAGKRRTTLHDRLENEVLPLFEGRLLPFDL
DASQAYADLMAQAKAAGRAIGKADGYIAATAAAHGLMVATRDTSPFEAAGVPIINPWETSD

Download         Length: 426 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9455.66 Da        Isoelectric Point: 5.7317

>AT259530 WP_262263165.1 NZ_CP104967:650967-651221 [Phyllobacterium sp. A18/5-2]
MATLTVRNLPEEVHRALRMRAATHGRSTEAEVRDILETTVRPPERVKLGSLLASIARDAGFNDAEAEQFDQLRDKTPAEP
VRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References